# Time-Restricted Eating and Symptom Severity in Irritable Bowel Syndrome: Results from a Pilot Study

**Authors:** Maria Thompson Clausen, Henrik Sverdrup, Asgeir Brevik, Marianne Molin, Marit Kolby

PMC · DOI: 10.3390/nu18050765 · Nutrients · 2026-02-26

## TL;DR

A pilot study found that time-restricted eating may reduce symptoms in people with irritable bowel syndrome.

## Contribution

This study is among the first to investigate TRE as a potential behavioral intervention for IBS symptom management.

## Key findings

- Participants showed a significant mean reduction in IBS Symptom Severity Scale scores after 8 weeks of TRE.
- Improvements were observed across all IBS subtypes (constipation, diarrhea, mixed).
- Participants also reported better physical and mental health.

## Abstract

Background/Objectives: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder affecting approximately 5–10% of the population, with many individuals reporting insufficient improvement from treatment options. This study aimed to explore whether time-restricted eating (TRE) could alleviate symptoms in patients with IBS. Methods: This single-group, pre–post pilot study included participants with IBS who followed an 8-week time-restricted eating protocol, defined as a daily 16 h fasting period and an 8 h eating window (16:8). Symptom changes were assessed using the validated IBS Symptom Severity Scale (IBS-SSS) at baseline and post-intervention. The study was retrospectively registered after completion of data collection. Results: A total of 134 patients were enrolled, of whom 97 completed the intervention. Participants demonstrated a mean reduction in the IBS-SSS score of −100.2 (p < 0.001). Subgroup analysis also demonstrated mean reductions in the IBS-SSS scores for participants with IBS-constipation (IBS-C) (−125.2, p < 0.001), IBS-diarrhea (IBS-D) (−76.0, p < 0.005), and IBS-mixed (IBS-M) (−93.1, p < 0.001). Additionally, the participants experienced improvements in both self-reported physical and mental health. Conclusions: These preliminary findings suggest that TRE may represent a promising behavioral strategy for IBS symptom management, warranting controlled trials.

## Linked entities

- **Diseases:** irritable bowel syndrome (MONDO:0005052)

## Full-text entities

- **Diseases:** constipation (MESH:D003248), IBS (MESH:D043183), gastrointestinal disorder (MESH:D005767), Symptom (MESH:D012816), diarrhea (MESH:D003967)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12987044/full.md

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Source: https://tomesphere.com/paper/PMC12987044