# A Study on Autonomous Driving Motion Sickness from the Perspective of Multimodal Human Signals

**Authors:** Su Young Kim, Yoon Sang Kim

PMC · DOI: 10.3390/s26051675 · Sensors (Basel, Switzerland) · 2026-03-06

## TL;DR

This study explores how multimodal human signals can help quantify motion sickness in autonomous driving, using data from a simulator and machine learning.

## Contribution

The study introduces a novel framework combining multimodal human signals and explainable machine learning to quantify motion sickness in autonomous driving.

## Key findings

- Head amplitude/energy correlates with oculomotor symptoms of motion sickness.
- EEG connectivity and head kinematics are major contributors to motion sickness prediction.
- A combination of head, PPG, and EDA signals retains high model interpretability.

## Abstract

In autonomous driving, motion sickness (MS) arises from physical or visual stimuli, or a combination of both. However, objective quantification of MS level (MSL) remains limited beyond questionnaire-based assessments. Using multimodal human signals (physiological and behavioral) collected in an autonomous driving simulator, this study addresses the association between these signals and MSL, across these MS types, by (i) screening and curating a decade of human-signal MS studies (HS-Set) to establish a data-driven foundation for selecting target sensor domains and features, (ii) constructing a dataset with subjective measures of MSL (fast motion sickness scale and simulator sickness questionnaire (SSQ)), alongside human signals (electroencephalogram (EEG), photoplethysmogram (PPG), electrodermal activity (EDA), skin temperature, and head/eye movement), (iii) conducting a correlation analysis between MSL and the identified features from HS-Set, and (iv) quantifying multivariable contributions at the feature and sensor domains through an explainable boosting machine (EBM). Key correlations include head amplitude/energy (pitch/surge) with SSQ total/oculomotor, eye entropy with nausea/oculomotor (positive), and EDA with nausea (negative). The EBM-based contribution analysis highlights EEG connectivity and head kinematics as dominant contributors; excluding EEG, the interpretability of single-domain models remains limited. Additionally, a combination of Head, PPG, and EDA domains retains over 80% of the full model’s interpretability.

## Full-text entities

- **Diseases:** nausea (MESH:D009325), MS (MESH:D009041)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

16 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12987010/full.md

## References

148 references — full list in the complete paper: https://tomesphere.com/paper/PMC12987010/full.md

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Source: https://tomesphere.com/paper/PMC12987010