Unlocking the Potential of Macroalgae: Innovative Pretreatment Strategies for Efficient Biorefinery
Xiucheng Gu, Ying Zhou

TL;DR
This review explores methods to break down macroalgae cell walls to improve their use in biorefineries for producing bioenergy and biochemicals.
Contribution
The paper systematically integrates pretreatment strategies and discusses genetic editing for enhancing macroalgal biorefinery efficiency.
Findings
Current pretreatment methods have varying effectiveness in overcoming macroalgal cell wall barriers.
Genetic editing tools like CRISPR-Cas can modify macroalgae to improve biorefinery traits.
Integrated industrial chains are crucial for advancing macroalgal biorefinery toward industrialization.
Abstract
Macroalgae represent a promising third-generation feedstock for biorefinery due to their high biomass productivity and non-reliance on arable land. However, their complex cell wall structure poses a significant barrier to efficient bioconversion. This review integrates current pretreatment methods, including physical, chemical, biological, and combined approaches, with a focus on their mechanisms, effectiveness, and limitations. Furthermore, it explores the conversion of pretreated macroalgal biomass into bioenergy and biochemicals, such as bioethanol, organic acid and polyhydroxyalkanoate, via microbial fermentation. The review also examines the application of genetic editing tools (e.g., CRISPR-Cas systems) for the targeted modification of macroalgae to improve their inherent characteristics for biorefinery, such as reducing biomass recalcitrance or increasing the content of target…
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Taxonomy
TopicsSeaweed-derived Bioactive Compounds · Marine and coastal plant biology · Plant Growth Enhancement Techniques
