Validation Analysis of the Polish-Translated Version of EmPHasis-10 Health-Related Quality of Life Questionnaire in Patients with Pulmonary Arterial Hypertension

TL;DR

The Polish version of the EmPHasis-10 questionnaire is a reliable and valid tool for measuring quality of life in patients with pulmonary arterial hypertension.

Contribution

The study validates the Polish translation of the EmPHasis-10 questionnaire for use in pulmonary arterial hypertension patients.

Findings

The Polish version of EmPHasis-10 has a unidimensional structure and high internal consistency (Cronbach α = 0.94).

The questionnaire shows adequate relationships with SF-36 and non-invasive prognostic factors like 6MWD and NTproBNP.

6MWD was identified as the only significant predictor of EmPHasis-10 scores.

Abstract

Background/Objectives: Pulmonary arterial hypertension (PAH) impacts various aspects of patients’ lives. Some questionnaires assessing health-related quality of life are specific to PAH patients. The aims of the study were to translate and investigate the factor structure and psychometric properties of the Polish version of the EmPHasis-10 health-related quality of life questionnaire in a group of adults with PAH. Construct validity was explored by the relationship with results of the 36-Item Short Form Survey (SF-36) and non-invasive prognostic factors: WHO functional class, 6 min walk distance (6MWD) and NTproBNP level were measured. Methods: In a single-center study, PAH patients were included. The diagnosis of PAH was confirmed by right heart catheterization. The demographic and clinical data were obtained. The EmPHasis-10 and the SF-36 questionnaires were administered to all patients. Results: Data from 120 PAH patients, median age 57 (IQR 45–68.7) years, 88 (73%) women, were obtained. Most of the patients suffered from IPAH (73, 61%). Results revealed a unidimensional structure of the EmPHasis-10 questionnaire and demonstrated satisfactory reliability (Cronbach α = 0.94). The EmPHasis-10 showed an adequate relationship with both SF-36 dimensions and three non-invasive prognostic parameters, i.e., WHO functional class, 6MWD and NTproBNP level. Regression analysis indicated that the 6MWD was the only predictor of the EmPHasis-10. Conclusions: The obtained results showed very good psychometric properties and adequate internal consistency of the Polish version of EmPHasis-10 in PAH patients. The results showed a unidimensional structure and very good psychometric properties, including satisfactory internal consistency and external validity of the Polish version of the EmPHasis-10 scale in patients with PAH.

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