Validation of the Formulas for Mechanical Power in Children and Proposal of the Concept of “Effective Mechanical Power”
María Ferrón-Vivó, Alicia Baza-Del-Amo, María J. Rupérez, Antonio Martínez-Millana, Ana M. Pedrosa, Roberto Tornero-Costa, Yolanda Rubio-Atienza, Marta Aguar-Carrascosa, Cristina Camilo, Alberto Medina, Vicent Modesto-i-Alapont
TL;DR
This study validates formulas for calculating mechanical power in children and introduces a new concept called 'effective mechanical power' to better estimate lung injury risk during ventilation.
Contribution
The study validates adult mechanical power formulas in children and proposes a novel concept of effective mechanical power with a new equation.
Findings
The simplified Gattinoni and generalized Giosa equations best estimate inspiratory mechanical power in children (R2 > 0.99).
The extended equation for expiratory mechanical power showed strong agreement with experimental results (R2 = 0.9954).
The simplified equation for effective mechanical power was most accurate (R2 = 0.9950).
Abstract
Background/Objectives: Recently, studies have emerged raising ergotrauma as a new explanation for ventilator-induced lung injury development, with the concept of inspiratory Mechanical Power (MP) as a single physical variable to estimate the contribution of different ventilatory parameters to lung damage. A high value of inspiratory MP is associated with risk of harming the respiratory system. Furthermore, we propose the concept of effective MP as the energy per minute that dissipates in the lungs, subtracting expiratory MP from inspiratory MP. Our objective is to validate the equations proposed for adults to estimate inspiratory MP in children, and to develop and validate equations to estimate effective MP. Methods: Prospective convenience sampling of 18 children undergoing mechanical ventilation in volume-controlled ventilation mode, admitted to the pediatric intensive care unit of a…
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Taxonomy
TopicsRespiratory Support and Mechanisms · Nosocomial Infections in ICU · Sepsis Diagnosis and Treatment