# The Future of Breast Cancer Treatment: From Conventional Wisdom to Nanotechnology-Enabled Precision

**Authors:** Neetika Kimta, Malak A. Majdalawieh, Amin F. Majdalawieh

PMC · DOI: 10.3390/ijms27052109 · International Journal of Molecular Sciences · 2026-02-24

## TL;DR

This paper reviews how nanotechnology and integrative medicine could improve breast cancer treatment by enhancing drug delivery and reducing side effects.

## Contribution

The paper introduces integrative approaches combining nanotechnology and traditional medicine to overcome limitations in breast cancer therapy.

## Key findings

- Green nanotechnology can transform Ayurvedic medicine into scientifically credible cancer treatments.
- Nanoparticles and nanorobotics offer potential for more effective and personalized breast cancer therapies.
- Integrative approaches may overcome challenges like drug resistance and systemic toxicity in conventional treatments.

## Abstract

Breast cancer remains a leading cause of mortality among women worldwide, presenting significant treatment challenges due to its aggressive nature and lack of targeted therapies. Traditional treatments, including surgery, radiation, and chemotherapy, have improved survival rates. However, limitations such as drug resistance and adverse side effects persist. Recent advancements in nanotechnology offer promising avenues for enhancing breast cancer treatment by improving drug delivery, increasing therapeutic efficacy, and minimizing systemic toxicity. This review explores breast cancer’s pathophysiology and molecular mechanisms, evaluates current diagnostic and therapeutic strategies, and discusses emerging innovations in nanotechnology and integrative medicine. Recent studies have demonstrated the efficacy of green nanotechnology in transforming Ayurvedic medicine into scientifically credible treatments. These integrative approaches not only enhance the therapeutic potential of traditional medicine but also offer a pathway to overcome challenges associated with conventional cancer treatments. The convergence of nanotechnology and traditional medical systems holds transformative potential in breast cancer therapy. By leveraging the unique properties of nanoparticles and nanorobotics, it is possible to develop more effective, personalized, and less toxic treatment modalities. Future research should optimize these integrative approaches, conduct rigorous clinical trials, and elucidate the underlying mechanisms to fully realize their potential in combating breast cancer.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** toxicity (MESH:D064420), cancer (MESH:D009369), Breast Cancer (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12984651/full.md

## References

187 references — full list in the complete paper: https://tomesphere.com/paper/PMC12984651/full.md

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Source: https://tomesphere.com/paper/PMC12984651