# Editorial: Lung Cancer—From Mechanisms of Action and Risk Factors in Disease Onset to Management

## TL;DR

This editorial introduces a collection of articles on lung cancer, covering risk factors, biomarkers, screening, and treatment strategies.

## Contribution

The collection emphasizes integrated, evidence-based approaches to address the complex nature of lung cancer.

## Key findings

- The collection includes research on risk factors like telomere biology and allostatic load.
- It highlights advances in biomarkers, screening, and treatment methods for lung cancer.
- The papers stress the need for multifaceted strategies to reduce lung cancer mortality.

## Abstract

Lung cancer is the leading cause of cancer-related mortality worldwide. This editorial accompanies the Special Issue “Lung Cancer: From Mechanisms of Action and Risk Factors in Disease Onset to Management” published in Cancers (MDPI), and introduces the twenty-one research and review articles included in the collection. The contributions span a wide spectrum of topics, from risk factors such as allostatic load and telomere biology, to molecular biomarkers including DNA methylation and serum glycopeptides, to advances in low-dose CT screening and the management of incidental findings, to targeted therapy, immunotherapy, surgical techniques, and health economics. Together, the papers highlight the multifactorial and clinically complex nature of lung cancer, and reinforce the importance of integrated, evidence-based strategies to reduce its global burden.