# A Rare Encounter: Mammary-Like Gland Tissue in an Anal Polyp

**Authors:** Laci-Rae Pitter, Sania L Siddiqui, Daniel Tomer, Jeffrey Snow, David Marshall, Gary Schwartz

PMC · DOI: 10.7759/cureus.103410 · 2026-02-11

## TL;DR

A rare case of mammary-like gland tissue found in an anal polyp is reported, highlighting the need for histologic evaluation to distinguish it from breast-related conditions.

## Contribution

This case report presents a rare occurrence of mammary-like glands outside the typical mammary line in the anogenital region.

## Key findings

- The anal polyp contained breast-like tissue with benign features such as intraductal papilloma and apocrine metaplasia.
- The case demonstrates that mammary-like glands can mimic breast lesions and require histologic confirmation for accurate diagnosis.
- Benign lesions in such cases can be managed conservatively or through excision based on symptoms and patient preference.

## Abstract

Anogenital mammary-like glands (AGMLGs) are normal structures in the anogenital region that can undergo pathologic changes similar to breast tissue. This case report presents a 54-year-old female with a complaint of worsening anorectal pain. Her initial physical exam revealed a 1 cm anal polyp. Pathology confirmed breast-like polypoid tissue with benign features, including intraductal papilloma, apocrine metaplasia, and fibrocystic change. The novelty of this case highlights that mammary-like glands can be found outside of the mammary line and may mimic lesions identical to counterparts in the native female breast, underlining that confirmation of diagnosis with histologic evaluation is crucial for management of rare benign and potentially malignant pathologies. Benign lesions can be conservatively excised or monitored based on symptoms and patient preference.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** anorectal pain (MESH:D010146), Anal Polyp (MESH:D011127), papilloma (MESH:D010212)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12983968/full.md

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Source: https://tomesphere.com/paper/PMC12983968