The role of clinical laboratory parameters in diabetic neuropathy: correlations and recent advances

TL;DR

This review explores how clinical lab tests can help predict and manage diabetic neuropathy, a common complication in diabetes.

Contribution

The paper provides a comprehensive overview of lab parameters linked to diabetic neuropathy, highlighting their potential for early diagnosis and personalized treatment.

Findings

Diabetic neuropathy is associated with metabolic, renal, and hepatic parameters.

Inflammatory biomarkers and vitamin levels correlate with neuropathy risk.

Combining multiple lab parameters may improve patient care and diagnosis.

Abstract

Diabetic neuropathy affects approximately 50% of patients with diabetes, causing significant health issues and reducing quality of life. This review examined the associations between diabetic neuropathy and various laboratory parameters, including metabolic indicators, renal and hepatic function parameters, inflammatory biomarkers, thyroid hormones and vitamins. By summarizing the latest evidence on these easily accessible clinical parameters, the article aims to improve risk stratification, enable earlier diagnosis and develop personalized therapeutic strategies, emphasizing the potential of multi-parameter biomarker integration to optimize patient care.

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