# Study Protocol: It is time to dig deeper: A cross-country implementation mapping study of the iFightDepression® (online self-management) tool

**Authors:** Thomas Rotter, Milica Petrovic, Mikołaj Zarzycki, Caroline Allenhof, Katharina Schnitzspahn, Piotr Toczyski, Azucena Justicia, Saiko Allende Leal, James Chan, Johannes Leimhofer, Katharina Scholze, Stefan Hackel, Victor Pérez Sola, Ulrich Hegerl

PMC · DOI: 10.1371/journal.pone.0343982 · 2026-03-12

## TL;DR

This study explores how to better implement an online depression management tool across three countries by identifying barriers and facilitators through surveys and focus groups.

## Contribution

The study introduces a cross-country implementation mapping approach using CFIR to improve uptake of the iFightDepression® tool.

## Key findings

- Barriers and facilitators to iFD tool adoption will be identified in Germany, Poland, and Spain.
- Country-specific implementation blueprints will be developed to improve uptake and adherence.
- Findings will inform a standardized iFD implementation manual.

## Abstract

The iFightDepression® (iFD) tool is an internet-based self-management program for individuals with milder forms of depression, used alongside support from trained user guides (e.g., family physicians). Despite strong evidence supporting guided internet-based cognitive behavioural therapy (iCBT), adherence to the iFD tool and its uptake across implementing countries remain variable.

This implementation mapping study will be conducted in Germany, Poland, and Spain. Guided by the Consolidated Framework for Implementation Research (CFIR), we aim to identify barriers, facilitators, and country-specific implementation strategies. In Phase 1, we will invite 15 trained iFD user guides to complete an online qualitative survey to explore user experiences and perceived influences on patient uptake and adherence. In Phase 2, three country-specific focus groups will be conducted with trained user guides (one in each country). Survey data will be analyzed using Interpretative Phenomenological Analysis (IPA) and focus group data will be analyzed using template analysis.

Findings will be used to develop an iFD implementation manual and country-specific implementation blueprints. These outputs are intended to support consistent and sustainable adoption of this internet-based intervention across participating countries and to improve patient uptake and adherence.

The study, including the analysis plan, has been preregistered via the Open Science Framework (internet archive link: https://archive.org/details/osf-registrations-wmbhy-v1) following ethical approval.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12981504/full.md

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Source: https://tomesphere.com/paper/PMC12981504