# Draft genome sequences of two multidrug-resistant Proteus mirabilis isolates from hospital wastewater and a discharge point into Manila Bay, Philippines

**Authors:** Shaughn Dominic M. Padon, Erica Mai T. Cabuyao, Nathaniel John Q. Cruz, Kiara Nicole D. Rodriguez, Leslie Michelle M. Dalmacio, Liza Bautista-Patacsil, Arnel B. Beltran, Aileen H. Orbecido, Joel C. Cornista

PMC · DOI: 10.1128/mra.01411-25 · 2026-02-24

## TL;DR

This paper presents draft genomes of two drug-resistant Proteus mirabilis strains found in hospital wastewater and Manila Bay.

## Contribution

The study provides new genomic data on multidrug-resistant Proteus mirabilis from environmental sources in the Philippines.

## Key findings

- P. mirabilis MA3 and MB8 have highly similar genomic features.
- The isolates were recovered from a hospital wastewater pathway and Manila Bay.
- The findings highlight environmental spread of drug-resistant bacteria.

## Abstract

Proteus mirabilis, causing community and hospital-acquired urinary tract infections, is implicated in multidrug resistance. We report the draft genomes of P. mirabilis MA3 and P. mirabilis MB8, both with highly similar genomic features, recovered from different points along a hospital wastewater pathway emptying into Manila Bay, a broader coastal environment.

## Linked entities

- **Species:** Proteus mirabilis (taxon 584), Mus musculus (taxon 10090)

## Full-text entities

- **Diseases:** urinary tract infections (MESH:D014552)
- **Species:** Proteus mirabilis (species) [taxon 584]

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Source: https://tomesphere.com/paper/PMC12981155