# Whole genome sequence of the syntrophic fatty acid-degrading bacterium Syntrophomonas curvata GB8-1T

**Authors:** Ethan Humm, Neil Q. Wofford, Jessica R. Sieber, Marco Morselli, Matteo Pellegrini, Michael J. McInerney, Sung Min Ha, Robert P. Gunsalus

PMC · DOI: 10.1128/mra.01525-25 · 2026-02-13

## TL;DR

This paper presents the complete genome sequence of Syntrophomonas curvata GB8-1T, a bacterium that breaks down fatty acids in partnership with other microbes under low-energy conditions.

## Contribution

The study provides the first complete genome sequence of this syntrophic fatty acid-degrading bacterium.

## Key findings

- The genome offers insights into fatty acid degradation under thermodynamically limiting conditions.
- The bacterium requires a hydrogenotrophic partner to metabolize C4–C18 fatty acids.
- The genome data may help understand syntrophic interactions in anaerobic environments.

## Abstract

The syntrophic fatty acid-degrading bacterium Syntrophomonas curvata strain GB8-1T, isolated from anaerobic granular sludge, metabolizes C4–C18 fatty acids when grown with a suitable hydrogenotrophic partner. The complete genome sequence data provide insight into syntrophic fatty acid compound degradation under thermodynamically limiting conditions when exogenous electron acceptors are absent.

## Linked entities

- **Species:** Syntrophomonas curvata (taxon 231025)

## Full-text entities

- **Chemicals:** fatty acid (MESH:D005227), C4-C18 fatty acids (-)

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Source: https://tomesphere.com/paper/PMC12981124