# Whole-genome sequencing of two clinical Staphylococcus haemolyticus isolates highlights antibiotic resistance genes and prophage elements

**Authors:** Fariza Shams, Syeda Naushin Tabassum, Aura Rahman, Nayma Haque Tonny, Pronoy Debnath, Asifa Siddika Badhon, Abdus Sadique, Jahidul Alam, Maqsud Hossain

PMC · DOI: 10.1128/mra.00773-25 · 2026-01-28

## TL;DR

This paper presents the whole-genome sequences of two Staphylococcus haemolyticus isolates, revealing antibiotic resistance genes and prophage elements important for understanding their virulence and drug resistance.

## Contribution

The study provides new whole-genome sequences of clinical S. haemolyticus isolates, highlighting resistance genes and prophage elements.

## Key findings

- The genomes of isolates NGCE 403 and FSCC13 were sequenced, revealing 2,533 and 2,586 genes respectively.
- The genomes contain antibiotic resistance genes and prophage elements that may contribute to virulence and resistance.

## Abstract

Staphylococcus haemolyticus is an emerging, multidrug-resistant pathogen associated with healthcare infections. We report the whole-genome sequences of two human isolates, NGCE 403 (2.6 Mb, 33% GC content, 2,533 genes) and FSCC13 (2.6 Mb, 32.5% GC content, 2,586 genes), which provide insights into their virulence and resistance mechanisms.

## Linked entities

- **Species:** Staphylococcus haemolyticus (taxon 1283)

## Full-text entities

- **Diseases:** infections (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Staphylococcus haemolyticus (species) [taxon 1283]

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Source: https://tomesphere.com/paper/PMC12981113