# Draft genome sequence of mangrove-isolated fungus Trichoderma reesei MA2 reveals potential antifungal compounds and other secondary metabolites

**Authors:** Alonso Segura-Valverde, Stefany Solano-González

PMC · DOI: 10.1128/mra.00720-25 · 2026-02-13

## TL;DR

The genome of a mangrove fungus reveals it can produce antifungal compounds and other useful chemicals.

## Contribution

The study presents a new genome sequence of T. reesei MA2 with potential for novel bioactive compounds.

## Key findings

- The genome is 33.4 Mb with 9,510 protein-coding genes.
- It contains 35 biosynthetic gene clusters for secondary metabolites.
- The fungus shows potential to produce antifungal compounds.

## Abstract

Trichoderma reesei MA2, isolated from Costarrican mangrove, exhibits biosynthetic potential to produce antifungal compounds and other secondary metabolites. The assembled genome was 33.4 Mb, with 9,510 protein-coding genes and 35 biosynthetic gene clusters, highlighting the potential of T. reesei MA2 as a source of unexplored bioactive compounds.

## Full-text entities

- **Chemicals:** antifungal compounds (-)

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Source: https://tomesphere.com/paper/PMC12981107