# Draft genome sequence of cadmium/zinc-resistant and virulent Staphylococcus aureus strain BHUSA01 isolated from a wound in Varanasi, India

**Authors:** Shweta Sinha, Sudhir Kumar Singh, Gopal Nath, Durg Vijai Singh

PMC · DOI: 10.1128/mra.00862-25 · 2026-02-03

## TL;DR

This paper presents the genome sequence of a Staphylococcus aureus strain from India that is resistant to cadmium, zinc, and antibiotics.

## Contribution

The study provides a draft genome sequence of a virulent and metal-resistant S. aureus strain from a clinical wound sample.

## Key findings

- The genome is 2.78 Mb with 32.66% GC content and 98.67% coverage.
- It contains genes for antibiotic resistance, virulence, biofilm formation, and cadmium/zinc resistance.

## Abstract

We report the draft genome sequence of Staphylococcus aureus strain BHUSA01, isolated from a patient’s wound (pus) at IMS, BHU, Varanasi. The genome is approximately 2.78 Mb in size, has GC content of 32.66%, and coverage of 98.67%, and contains antibiotic resistance, virulence, biofilm-related, and cadmium/zinc resistance genes.

## Linked entities

- **Species:** Staphylococcus aureus (taxon 1280)

## Full-text entities

- **Chemicals:** cadmium (MESH:D002104), zinc (MESH:D015032)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12981097/full.md

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Source: https://tomesphere.com/paper/PMC12981097