# Genomes of Syntrophomonas erecta GB4-38T and Syntrophomonas erecta subsp. sporosyntropha 5-3-ZT that degrade C4-8 short-chain fatty acids

**Authors:** Sung Min Ha, Ethan Humm, Neil Q. Wofford, Jessica R. Sieber, Liudmilla Rubbi, Giorgia del Vecchio, Matteo Pellegrini, Michael J. McInerney, Robert P. Gunsalus

PMC · DOI: 10.1128/mra.01419-25 · 2026-02-12

## TL;DR

This paper presents the genome sequences of two bacteria that work with other microbes to break down short-chain fatty acids.

## Contribution

The study provides new genome sequences for two Syntrophomonas erecta subspecies involved in syntrophic degradation of fatty acids.

## Key findings

- The genomes of Syntrophomonas erecta GB4-38T and Syntrophomonas erecta subsp. sporosyntropha 5-3-ZT were sequenced.
- These bacteria degrade C4-C8 fatty acids in co-culture with hydrogen-consuming microbes.

## Abstract

We report the genome sequences of two syntrophic gram-negative bacteria, Syntrophomonas erecta GB4-38T and Syntrophomonas erecta subsp. sporosyntropha 5-3-ZT, which degrade C4-C8 short-chain fatty acids when grown in co-culture with a suitable hydrogen-consuming microbial strain.

## Full-text entities

- **Chemicals:** hydrogen (MESH:D006859), 5-3-ZT (-)

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Source: https://tomesphere.com/paper/PMC12981089