# Whole genome sequences of novel Staphylococcus epidermidis, Streptococcus salivarius, and Streptococcus anginosus strains isolated from human gastric biopsy tissue

**Authors:** Anthony Mannion, Zeli Shen, JoAnn Dzink-Fox, M. Blanca Piazuelo, Keith T. Wilson, Richard M. Peek, James G. Fox

PMC · DOI: 10.1128/mra.01136-25 · 2026-02-19

## TL;DR

Researchers sequenced three new bacteria strains from human stomach tissue to understand their role in gastric cancer risk.

## Contribution

The study provides whole genome sequences of three novel bacterial strains from gastric biopsy samples.

## Key findings

- Staphylococcus epidermidis, Streptococcus salivarius, and Streptococcus anginosus strains were isolated from gastric biopsies.
- Genome sequencing was performed to explore their potential pathogenic or protective roles.
- The strains were sequenced using Illumina MiSeq for phylogenetic analysis.

## Abstract

Three novel bacterial strains, Staphylococcus epidermidis, Streptococcus salivarius, and Streptococcus anginosus, were cultured from human gastric biopsy tissue from Colombian, South America patients with a high risk for gastric cancer. Bacteria were sequenced using Illumina MiSeq technology for phylogenetic characterization and identification of genetic mechanisms conferring pathogenic or protective potential.

## Linked entities

- **Diseases:** gastric cancer (MONDO:0001056)
- **Species:** Staphylococcus epidermidis (taxon 1282), Streptococcus salivarius (taxon 1304), Streptococcus anginosus (taxon 1328)

## Full-text entities

- **Diseases:** gastric cancer (MESH:D013274)
- **Species:** Staphylococcus epidermidis (species) [taxon 1282], Homo sapiens (human, species) [taxon 9606], Streptococcus salivarius (species) [taxon 1304], Streptococcus anginosus (species) [taxon 1328]

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Source: https://tomesphere.com/paper/PMC12981082