# Draft genome sequence of a carbapenem-resistant Pseudomonas aeruginosa strain PA1, a clinical isolate from Bangladesh

**Authors:** Fahd B. Zahed, Tangerul A. Jepu, M. Ismail Hossain, Fatema T. Zohora, Tasmim A. Saleh, Nusrat U. A. Saleh, M. Salah Uddin, Muktadir S. Hossain

PMC · DOI: 10.1128/mra.01211-25 · 2026-02-18

## TL;DR

This paper presents the draft genome sequence of a drug-resistant Pseudomonas aeruginosa strain from Bangladesh, highlighting its resistance and virulence genes.

## Contribution

The novel contribution is the genome sequencing and characterization of a carbapenem-resistant Pseudomonas aeruginosa strain from a clinical isolate in Bangladesh.

## Key findings

- The PA1 strain has a 6.4 Mbp draft genome with multiple virulence and antibiotic-resistance genes.
- PA1 belongs to ST1650 and shares >99.1% ANI with the reference strain PAO1.

## Abstract

Pseudomonas aeruginosa strain PA1, a multidrug-resistant opportunistic pathogen that was isolated from Dhaka, Bangladesh, has a 6.4 Mbp draft genome. The key features include the presence of multiple virulence genes and a number of antibiotic-resistance genes. PA1 belongs to ST1650, with >99.1% ANI to PAO1.

## Linked entities

- **Species:** Pseudomonas aeruginosa (taxon 287)

## Full-text entities

- **Genes:** SMOX (spermine oxidase) [NCBI Gene 54498] {aka C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1}
- **Chemicals:** carbapenem (MESH:D015780)
- **Species:** Pseudomonas aeruginosa (species) [taxon 287], Pseudomonas aeruginosa PA1 (strain) [taxon 1279007]

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Source: https://tomesphere.com/paper/PMC12981064