# Eccrine Syringofibroadenoma: A Rare Case of Benign Appendageal Tumor

## TL;DR

This paper presents a rare case of a benign skin tumor called eccrine syringofibroadenoma, emphasizing the importance of accurate diagnosis and treatment.

## Contribution

The paper contributes a detailed case report of ESFA with dermoscopic and histopathological findings, aiding in clinical recognition.

## Key findings

- Dermoscopy showed light-brown pigment globules in a cobblestone pattern with yellowish scales and central crusting.
- Histopathology confirmed the diagnosis of ESFA with anastomosing epithelial cords in a mucin-rich fibrovascular stroma.
- Complete surgical excision led to an excellent clinical outcome.

## Abstract

Eccrine syringofibroadenoma (ESFA) is a rare benign adnexal neoplasm characterized by eccrine ductal differentiation within a fibrovascular stroma and poses significant diagnostic challenges due to its variable clinical presentation. It may occur as a solitary lesion, a reactive proliferation in chronically inflamed or traumatized skin, or in association with hereditary syndromes. We report a case of a 47-year-old male presenting with a two-year history of asymptomatic, slowly enlarging nodules forming an annular plaque over the posterolateral aspect of the right foot. Dermoscopy revealed light-brown pigment globules in a cobblestone pattern with yellowish scales and central crusting. Histopathology demonstrated anastomosing epithelial cords with eccrine ductal differentiation embedded in a mucin-rich fibrovascular stroma, confirming ESFA. The lesion was treated with complete surgical excision, resulting in an excellent outcome. This case highlights the importance of clinicopathological correlation, the supportive role of dermoscopy, and the need for awareness of ESFA in chronic acral lesions.