# From pedigrees to practicality: an interactive tool for cat breeding

## TL;DR

This paper introduces pawlineR, a browser-based tool that helps cat breeders calculate inbreeding coefficients and manage genetic diversity more effectively.

## Contribution

The novelty lies in providing an accessible, real-time tool for calculating inbreeding coefficients and simulating breedings for cat breeders.

## Key findings

- pawlineR accurately calculates inbreeding coefficients using Wright’s formula when pedigree data is complete.
- The tool identified 24 out of 70 cats with moderate to high inbreeding values (0.063–0.375).
- Virtual breedings enable breeders to simulate mating outcomes and assess inbreeding risks before actual matings.

## Abstract

Breeding programs for companion animals are increasingly relying on accurate inbreeding coefficients to maintain genetic diversity and limit the occurrence of deleterious traits. To bridge the gap between advanced genetic tools and everyday breeder practice, we developed pawlineR, a streamlined, browser-based application that leverages R libraries to automate pedigree entry, validate parent-offspring relationships, and calculate the inbreeding coefficient (F) in real time. A historical dataset of 70 cats was used to evaluate the tool (pawlineR). Among these animals, 24 showed moderate to high inbreeding values (0.063–0.375). “Virtual breedings” allow users to simulate hypothetical offspring and test potential inbreeding risks before committing to real matings, promoting proactive decision-making. Manual validation using Wright’s formula confirmed the accuracy of the tool’s calculations. Accuracy depends on pedigree completeness. By offering user-friendly interfaces and stable, long-term pedigree storage, this application helps cat breeders track F across generations. Overall, the tool reduces technical barriers, supports routine breeding management, and can be extended to other species.