# The sophist in the server: Rhetoric, Reasoning and Scientific Judgment in the Age of LLMs

**Authors:** Maria T Colangelo, Carlo Galli

PMC · DOI: 10.1038/s44319-026-00711-w · EMBO Reports · 2026-02-06

## TL;DR

This paper discusses how large language models can convincingly argue both sides of an issue, which may blur the line between persuasive rhetoric and scientific evidence.

## Contribution

The paper introduces a critical analysis of how LLMs impact scientific judgment and proposes ways to maintain rigorous standards in research.

## Key findings

- LLMs can generate equally persuasive arguments for conflicting hypotheses.
- This capability risks confusing rhetorical skill with scientific validity.
- Scientists must balance LLM fluency with epistemic discipline.

## Abstract

Large language models can defend a hypothesis and its opposite with equal eloquence, raising a new risk for scientific reasoning: confusing rhetorical plausibility with evidential support. This essay analyzes how LLMs reshape creativity, judgment and responsibility in research—and how scientists can engage their fluency without surrendering epistemic discipline.

## Full-text entities

- **Diseases:** LLM (MESH:D007806)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12979577/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12979577/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12979577/full.md

---
Source: https://tomesphere.com/paper/PMC12979577