# Spinal schwannoma missed on lumbar MRI: a case report

**Authors:** Pengfei Zhang, Ziyuan Zhang, Wenqin Sun

PMC · DOI: 10.3389/fmed.2026.1741404 · Frontiers in Medicine · 2026-02-26

## TL;DR

A 55-year-old man with persistent back and leg pain was found to have a spinal schwannoma initially missed on MRI, highlighting the importance of advanced diagnostic techniques and specialized surgery.

## Contribution

This case report highlights the diagnostic challenges of spinal schwannoma and the effectiveness of arthroscopic-assisted endoscopic surgery for treatment.

## Key findings

- Lumbar schwannoma can mimic disk herniation or cysts on MRI, leading to misdiagnosis.
- Contrast-enhanced MRI and selective nerve root blocks are critical for accurate diagnosis.
- Arthroscopic-assisted endoscopic resection effectively resolved symptoms and confirmed the schwannoma diagnosis.

## Abstract

A 55-year-old male presented with 9 months of left buttock and lower limb pain, initially misdiagnosed as lumbar disk herniation. Unsuccessful lateral recess block and physical therapy prompted further evaluation. Lumbar magnetic resonance imaging (MRI) revealed a right L5 nerve root cyst, yet symptoms worsened. Examination showed left paraspinal tenderness, grade IV left lower limb weakness, hyperesthesia, and positive straight leg raise tests. Selective nerve root block localized the lesion to the left L5 root; contrast-enhanced MRI identified an L4-5 facet joint cyst with inflammation. Arthroscopic-assisted Uni-portal Spinal Surgery (AUSS) endoscopic resection under general anesthesia was performed, with pathology confirming schwannoma. Postoperatively, pain intensity (numerical rating scale, NRS) decreased from 7 to 2 within 24 h; discharge occurred on day 6. At 2-month follow-up, symptoms resolved completely. This case underscores the diagnostic pitfalls of lumbar schwannoma (mimicking disk herniation/cysts) and highlights the roles of nerve root blocks, contrast MRI, and histopathology. AUSS endoscopy achieved definitive management.

## Linked entities

- **Diseases:** schwannoma (MONDO:0002546)

## Full-text entities

- **Diseases:** paraspinal tenderness (MESH:D063806), disk herniation (MESH:D007405), inflammation (MESH:D007249), nerve root cyst (MESH:D011843), cysts (MESH:D003560), Spinal schwannoma (MESH:D009442), Lumbar (MESH:C563613), pain (MESH:D010146), lower limb weakness (MESH:D018908)

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12979521/full.md

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Source: https://tomesphere.com/paper/PMC12979521