# Early Predictors of the Childhood Dysregulation Profile: A Systematic Review

**Authors:** Elzbieta Vitkauskaite, Ayten Bilgin

PMC · DOI: 10.1007/s10567-026-00557-7 · Clinical Child and Family Psychology Review · 2026-02-06

## TL;DR

This review explores early life factors that predict childhood dysregulation, focusing on family and child-related influences.

## Contribution

The study systematically identifies early predictors of childhood dysregulation profile symptoms.

## Key findings

- Family factors like parental mental health and social adversity are linked to childhood DP symptoms.
- Child-related factors such as difficult temperament and early regulatory problems predict DP symptoms.
- Evidence on birth weight, gestational age, and cognitive development remains inconclusive.

## Abstract

Childhood dysregulation profile (DP) involves difficulties in regulating emotions, behaviour and cognitions, and is associated with adverse long-term outcomes, yet its early life predictors are less well understood. This systematic review examined peer-reviewed studies published in English up to December 2024, identifying 12 eligible articles. Findings revealed that family-related factors such as parental mental health symptoms, lower education, prenatal substance use, and higher social adversity were associated with increased childhood DP symptoms, whereas evidence on parenting behaviours and home environment was inconclusive. Among child-related predictors, boys, children with difficult temperaments, and those with early regulatory problems (i.e., excessive crying, sleeping or feeding problems) were more likely to show childhood DP symptoms. On the other hand, the impacts of low birth weight, and gestational age were inconclusive. Research on the influence of language, cognitive skills and early social development remains limited. Further prospective longitudinal studies are needed to strengthen the evidence base.

## Full-text entities

- **Diseases:** post-traumatic stress disorder (MESH:D013313), self (MESH:D012652), ODD (MESH:D019958), aggression (MESH:D010554), Bipolar (MESH:D001714), dissocial disorders (MESH:D004213), mental health (OMIM:603663), autism spectrum disorder (MESH:D000067877), anxiety (MESH:D001007), social anxiety (MESH:D000072861), major depression (MESH:D003865), ADHD (MESH:D001289), conduct problems (MESH:D019973), SDQ (MESH:D051346), eating disorder (MESH:D001068), preterm birth (MESH:D047928), CBCL (MESH:C562515), phobia (MESH:D010698), dysthymia (MESH:D019263), panic (MESH:D016584), anxious/depressed (MESH:D003866), schizophrenia (MESH:D012559), inattention (MESH:D001308), DP (MESH:D021081), hyperactivity (MESH:D006948), maternal distress (MESH:D012128), mental health problems (MESH:D000076082), alcoholism (MESH:D000437), Disruptive Mood Dysregulation Disorder (MESH:D019964), impulsiveness (MESH:D007174), internalizing problems (MESH:D000082122), Mental Disorders (MESH:D001523), anxiety disorder (MESH:D001008), obsessive-compulsive disorder (MESH:D009771), Substance Use (MESH:D019966)
- **Chemicals:** DP (-), alcohol (MESH:D000438), nicotine (MESH:D009538)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nicotiana tabacum (American tobacco, species) [taxon 4097]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12979413/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12979413/full.md

---
Source: https://tomesphere.com/paper/PMC12979413