# The effects of orally ingested Delta-9-Tetrahydrocannabinol on drivers’ hazard perception and risk-taking behaviours: A within-subjects study of medicinal cannabis users

**Authors:** Taren Mieran, Andrew Hill, Mark S. Horswill, Mathew J. Summers, Kayla B. Stefanidis

PMC · DOI: 10.1007/s00213-025-06869-w · Psychopharmacology · 2025-07-31

## TL;DR

This study examines how oral THC affects driving skills and risk behaviors in medicinal cannabis users, finding no decline in hazard perception but altered self-perception and compensatory driving strategies.

## Contribution

The study provides new insights into how medicinal cannabis users adjust their driving behaviors after THC consumption.

## Key findings

- THC consumption did not significantly reduce hazard perception skill performance in medicinal cannabis users.
- Participants selected slower speeds and longer following distances after consuming THC.
- Users were unable to accurately self-assess their hazard perception performance, regardless of THC consumption.

## Abstract

Medicinal cannabis use is increasing worldwide, yet its impacts on driving safety in frequent users are not clearly understood. A more comprehensive understanding of the effects of THC on driving behaviour in frequent users is needed to guide drug driving policy and evidence-based advice for medicinal cannabis consumers. This study investigated the acute effects of orally ingested THC oil on medicinal cannabis users’: (a) hazard perception skill performance; (b) driving-related risk-taking behaviours (speeding propensity, following distance, gap acceptance); (c) self-perceived hazard perception skill performance; and (d) self-perceptions of driving skills and safety. A within-subjects design was used to compare scores on validated video-based measures of hazard perception skill and risk-taking behaviours, along with self-report measures, between baseline (no THC) and post-consumption. Although participants’ (N = 41) actual hazard perception skill performance did not significantly decline from baseline to post-consumption, their perceived performance did (with no significant correlation between the two in either condition). In the other video-based measures, participants selected significantly slower speeds and longer following distances post-consumption (but gap acceptance behaviour was unchanged). There was no significant change in self-perceptions of driving skills and safety after correction for multiple tests. While there was no evidence that oral ingestion of THC oils by medicinal cannabis users impacted hazard perception skill performance, they were unable to accurately self-assess their performance, regardless of whether they had consumed THC. Further, medicinal cannabis patients engage in compensatory strategies, specifically by reducing their speed and increasing their following distance following the consumption of THC.

## Linked entities

- **Chemicals:** Delta-9-Tetrahydrocannabinol (PubChem CID 2978), THC (PubChem CID 16078)

## Full-text entities

- **Chemicals:** THC oil (-), Delta-9-Tetrahydrocannabinol (MESH:D013759)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12979314/full.md

## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12979314/full.md

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Source: https://tomesphere.com/paper/PMC12979314