# Early Spontaneous Common Bile Duct Perforation

**Authors:** Eugenia Yoo, Alana M Hofmann, Ralph C Quillin, Christopher B Horn

PMC · DOI: 10.7759/cureus.103292 · 2026-02-09

## TL;DR

A rare case of spontaneous bile duct perforation in an adult is reported, emphasizing the importance of considering alternative diagnoses in similar clinical scenarios.

## Contribution

This paper presents a rare case of spontaneous CBD perforation in an adult, highlighting diagnostic and management challenges.

## Key findings

- CBD perforation occurred in a 59-year-old woman with acute perforated cholecystitis and pancreatitis.
- The case was managed with endoscopic stent placement and delayed cholecystectomy.
- Short symptom duration before perforation underscores the need for increased diagnostic suspicion.

## Abstract

Non-iatrogenic, non-traumatic common bile duct (CBD) perforation is a rare finding in the adult population and is more commonly reported in the pediatric population. Etiologies of CBD perforation in adults include traumatic injury, increased intraductal pressure due to choledocholithiasis, and biliary duct necrosis from underlying inflammation such as chronic pancreatitis. We present the case of a 59-year-old woman who initially presented with acute perforated cholecystitis with pancreatitis with intra-operative findings of a CBD perforation, which is not well-described in the literature. Management included endoscopic retrograde cholangiopancreatography with CBD stent placement and delayed cholecystectomy. This case is notable for the short period of symptoms prior to perforation and highlights the need for a higher degree of suspicion for alternative diagnoses when confronted with perforated cholecystitis.

## Linked entities

- **Diseases:** choledocholithiasis (MONDO:0006699), chronic pancreatitis (MONDO:0005003)

## Full-text entities

- **Diseases:** perforated cholecystitis (MESH:D002764), pancreatitis (MESH:D010195), common bile duct (CBD (MESH:D003137), inflammation (MESH:D007249), traumatic (MESH:D014947), biliary duct necrosis (MESH:D009336), perforation (MESH:D057112), chronic pancreatitis (MESH:D050500), choledocholithiasis (MESH:D042883), CBD perforation (MESH:D003138)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12978511/full.md

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Source: https://tomesphere.com/paper/PMC12978511