# Effects of interactivity, immersion, and physical discomfort on learning in VR nursing education

**Authors:** Yu-Chia Chang, Yi-Ting Lo, Cheng-Chia Yang, Muhammad Shahid Anwar, Muhammad Shahid Anwar, Muhammad Shahid Anwar

PMC · DOI: 10.1371/journal.pone.0344586 · 2026-03-11

## TL;DR

This study explores how VR features like interactivity and immersion affect learning in nursing education, finding that interactivity is more important than immersion for learning outcomes.

## Contribution

The study introduces a novel analysis of how interactivity, immersion, and physical discomfort influence learning in VR nursing education.

## Key findings

- Interactivity has stronger positive effects on self-efficacy, motivation, and learning than immersion.
- Visual discomfort negatively impacts immersion and interactivity, especially for younger and female users.
- Physical discomfort like NSB pain is positively linked to immersion but not interactivity.

## Abstract

Although VR provides innovative opportunities for nursing education, little is known about how its core features immersion and interactivity shape learners’ self-efficacy, motivation, and cognitive processes. Furthermore, the impact of physical discomfort during VR use remains underexplored. This study investigates the effects of immersion and interactivity on affective and cognitive constructs in nursing education using virtual reality (VR), while examining the influence of physical discomfort and the moderating roles of age and gender.

A cross-sectional study was conducted with 209 students (aged ≥20 years) recruited from three nurse aide training centers in Taiwan. The research team developed a VR training system using Unity 3D and Autodesk 3DS Max, incorporating three essential nursing skills: Heimlich maneuver, meal preparation/feeding/medication assistance, and vital sign measurement. After completing the VR training, participants filled out structured questionnaires. Data were analyzed using partial least squares structural equation modeling (PLS-SEM).

Interactivity showed stronger positive associations than immersion with self-efficacy, intrinsic motivation, situational interest, and embodied learning, and was associated with lower levels of extraneous cognitive load. Visual discomfort was negatively associated with both immersion and interactivity, whereas neck, shoulder, and back (NSB) pain was positively associated with immersion. Multi-group analysis revealed that female participants reported greater visual discomfort, which reduced immersion and interactivity. Additionally, participants under 35 years old exhibited greater sensitivity to visual discomfort in relation to immersion compared with older participants.

Interactivity is more crucial than immersion for enhancing affective and cognitive learning outcomes in VR-based nursing education. Visual discomfort significantly impairs learning experiences, with stronger negative effects among female and younger users, suggesting the need for further attention to user characteristics and physical comfort in VR-supported nursing education.

## Full-text entities

- **Diseases:** headache (MESH:D006261), Limb Pain (MESH:D010146), blurred vision (MESH:D014786), NSB) pain (MESH:D020069), Head Discomfort (MESH:D006258), nausea (MESH:D009325), Musculoskeletal pain (MESH:D059352), fatigue (MESH:D005221), eye strain (MESH:D013180), NSB (MESH:D000070599), NTD (MESH:D009436), COVID-19 (MESH:D000086382), dizziness (MESH:D004244), eyestrain (MESH:D001248), musculoskeletal discomfort (MESH:D009140), dryness (MESH:D014987), neuropsychiatric, cardiovascular, cognitive, and sensory disorders (MESH:D003072)
- **Chemicals:** PONE-D-25-54729R1 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** 3D with C

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12978480/full.md

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Source: https://tomesphere.com/paper/PMC12978480