# The Human Organ Atlas

**Authors:** Claire L. Walsh, Joseph Brunet, David Stansby, Guillaume Gaisné, Yang Zhou, Maximilian Ackermann, Alexandre Bellier, Camille Berruyer, Axel Bocciarelli, Marjolaine Bodin, Bernadette S. de Bakker, Hector Dejea, Alejandro De Maria Antolinos, Klaus Engel, Andy Götz, Joseph Jacob, Daniel Jonigk, Joanna Purzycka, Theresa Urban, Stijn E. Verleden, Ruikang Xue, Paul Tafforeau, Peter D. Lee

PMC · DOI: 10.1126/sciadv.adz2240 · 2026-03-11

## TL;DR

The Human Organ Atlas is an open-access resource offering 3D images of human organs at multiple scales, aiding research and education.

## Contribution

The HOA introduces a new open data repository with multiscale 3D imaging and tools for anatomical exploration.

## Key findings

- HOA provides whole-organ imaging at ~20 micrometers/voxel and substructures at ~1 micrometer/voxel.
- The repository includes software tools and training resources for global access and analysis.
- HOA supports anatomical study, medical education, and data mining with its comprehensive 3D imaging.

## Abstract

We present the Human Organ Atlas (HOA), an open data repository making accessible multiscale three-dimensional imaging of human organs. The repository also provides software tools and training resources enabling worldwide access, sharing, and analysis of these datasets, facilitating further research and the continued expansion of the HOA. The images are generated using a synchrotron imaging technique, hierarchical phase-contrast tomography (HiP-CT), that uses the ESRF’s Extremely Brilliant Source, spanning whole-organ imaging at ~20 micrometers/voxel with local volumes of interest within intact organs imaged down to ~1 micrometer/voxel. This offers a comprehensive exploration of human anatomy, providing unparalleled insights into intricate structures and spatial relationships. The HOA offers researchers, clinicians, and educators a valuable resource for anatomical study, image analysis, medical education, and large-scale data mining.

The Human Organ Atlas provides open access to 3D images of human anatomy spanning whole organs to cellular scale resolution.

## Full-text entities

- **Diseases:** disease (MESH:D004194), cancer (MESH:D009369), congenital malformation of the cerebellum (MESH:D002526), congenital airway malformation (MESH:D000402), death (MESH:D003643), hypertension (MESH:D006973), COVID-19 (MESH:D000086382), HOA (MESH:D000092124), Dandy-Walker syndrome (MESH:D003616)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A129, C to E, F to I

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12978218/full.md

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Source: https://tomesphere.com/paper/PMC12978218