# Fetal Long QT Syndrome: Case Series and Literature Review With Focus on Multidisciplinary Care Coordination

**Authors:** Stefani Samples, Sara Cherny, Stephanie Chandler, Ronald T. Wakai, Janette F. Strasburger, Sheetal Patel

PMC · DOI: 10.1155/cric/5600959 · 2026-03-11

## TL;DR

This paper discusses managing fetal long QT syndrome through a multidisciplinary team to improve outcomes for mothers and babies.

## Contribution

The study presents a case series and emphasizes the importance of coordinated multidisciplinary care in prenatal LQTS management.

## Key findings

- Five cases of fetal LQTS diagnosis with varied presentations and management strategies are described.
- A multidisciplinary team approach improved prenatal and postnatal outcomes for affected infants and mothers.

## Abstract

Congenital long QT syndrome (LQTS) is a group of heritable conditions that are associated with cardiac repolarization abnormality characterized by QT prolongation on ECG and risk of life‐threatening arrhythmias. Prenatal detection of LQTS presents many challenges for clinicians and a multidisciplinary approach is needed for optimal prenatal and postnatal management. We describe five cases of fetal diagnosis of LQTS with variable initial presentation, diagnostic strategies, and management approaches. A multidisciplinary team approach including fetal cardiologist, adult and pediatric electrophysiologists, medical physicists, neonatologists, maternal–fetal medicine specialists, fetal cardiac nurse coordinators, and genetic counselors allowed for comprehensive prenatal management and well‐planned postnatal treatment to optimize neonatal and maternal outcomes.

## Linked entities

- **Diseases:** long QT syndrome (MONDO:0002442), congenital long QT syndrome (MONDO:0019171)

## Full-text entities

- **Diseases:** arrhythmias (MESH:D001145), cardiac repolarization abnormality (MESH:D018376), Congenital long QT syndrome (MESH:D008133)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12976972/full.md

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Source: https://tomesphere.com/paper/PMC12976972