# Large Nonfunctioning Anterior Mediastinal Epiaortic Paraganglioma

**Authors:** Batoul Abbas, Aya Alhelou, Eman Darrh, Batool Marwa, Albaraa Bara, Mohammad Bashar Izzat

PMC · DOI: 10.1155/cric/4216128 · 2026-03-11

## TL;DR

This paper reports a rare case of a patient with two different paragangliomas, requiring aortic replacement and highlighting the need for thorough screening.

## Contribution

The novelty lies in the rare coexistence of a carotid body tumor and a large nonfunctioning epiaortic paraganglioma requiring aortic surgery.

## Key findings

- A patient had a carotid body tumor and a large nonfunctioning epiaortic paraganglioma.
- The case required ascending aorta replacement due to the tumor's location.
- Extrathoracic neuroendocrine tumors should prompt screening for multiple tumors.

## Abstract

We present a very rare case of a carotid body tumor accompanied by a large nonfunctioning epiaortic paraganglioma requiring ascending aorta replacement. Even though multiple paragangliomas in different locations in a single patient are highly uncommon, preoperative discovery of an extrathoracic neuroendocrine tumor should prompt full screening for the presence of multiple tumors.

## Linked entities

- **Diseases:** paraganglioma (MONDO:0000448)

## Full-text entities

- **Diseases:** carotid body tumor (MESH:D002345), Epiaortic Paraganglioma (MESH:D010235), neuroendocrine tumor (MESH:D018358), tumors (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12976970/full.md

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Source: https://tomesphere.com/paper/PMC12976970