# Isolated Septal Branch Occlusion Causing Septal Myocardial Infarction, With Suspected Embolic Etiology From Left Atrial Appendage Thrombus: A Case Report

**Authors:** A. Jano, A. Hamadanchi, A. Große, P. C. Schulze, R. Surber

PMC · DOI: 10.1155/cric/6815054 · 2026-03-11

## TL;DR

A 76-year-old woman with atrial fibrillation had a heart attack caused by a blood clot from her left atrial appendage, highlighting the need for proper anticoagulation.

## Contribution

This case report presents a rare instance of septal myocardial infarction caused by embolic occlusion from a left atrial appendage thrombus.

## Key findings

- The patient's septal myocardial infarction was linked to a thrombus in the left atrial appendage.
- Discontinued anticoagulation therapy likely contributed to clot formation and subsequent embolism.

## Abstract

We present a case of a 76‐year‐old female who experienced an isolated embolic occlusion of the septal branch, resulting in a septal myocardial infarction (MI) due to a thrombus in the left atrial appendage (LAA). The patient′s history included atrial fibrillation (AF), multiple allergies, and a self‐discontinued anticoagulation regimen. This case underscores the importance of anticoagulation therapy in AF patients and highlights the challenges of managing patients with complex medical histories and medication intolerances.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** Left Atrial Appendage Thrombus (MESH:D013927), MI (MESH:D009203), AF (MESH:D001281), allergies (MESH:D004342), embolic occlusion (MESH:D004617)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12976810/full.md

---
Source: https://tomesphere.com/paper/PMC12976810