# Follicular Thyroid Carcinoma Metastasis to the Retromolar Trigone: A Case Report

**Authors:** Homood M Almutairy, Hassan Alshurafa, Meshal Alsaedi, Yazieed M Albarrak, Rawan M Alahmadi, Fareed R AlGhamdi, Alyaa S Al Mutairy, Yazeed A Alkhalifah

PMC · DOI: 10.7759/cureus.103245 · 2026-02-08

## TL;DR

A rare case of follicular thyroid carcinoma metastasizing to the retromolar trigone in a patient with a history of thyroid cancer is reported, highlighting the need for vigilance in unusual oral lesions.

## Contribution

This case report adds to the limited literature on FTC metastasis to the retromolar trigone and emphasizes diagnostic considerations in such atypical presentations.

## Key findings

- A 48-year-old woman with prior FTC treatment presented with a retromolar mass confirmed as metastatic FTC.
- Conservative surgery and radioactive iodine therapy led to complete resolution of the lesion with no recurrence after six months.

## Abstract

Follicular thyroid carcinoma (FTC) may occasionally present with metastatic disease at atypical oral sites. This report describes a case of FTC involving the retromolar trigone. A 48-year-old woman with a history of FTC treated a decade earlier with total thyroidectomy and radioactive iodine therapy presented with a two-month history of a mass in the left retromolar region. Histopathological analysis of an incisional biopsy confirmed a metastatic well-differentiated follicular thyroid carcinoma. A conservative surgical approach involving left-sided modified radical neck dissection, followed by radioactive iodine management, caused complete resolution of the patient’s retromolar lesion. Follow-up over six months showed no evidence of recurrence. This case highlights a rare presentation of FTC metastasizing to the retromolar trigone. It underscores the importance of maintaining a high index of suspicion for metastatic disease in unusual oral lesions in patients with a history of thyroid cancer.

## Linked entities

- **Diseases:** Follicular thyroid carcinoma (MONDO:0005034), metastatic disease (MONDO:0024883)

## Full-text entities

- **Diseases:** FTC (MESH:D018263), oral lesions (MESH:D009059), metastatic disease (MESH:D000092182), Metastasis (MESH:D009362), thyroid cancer (MESH:D013964)
- **Chemicals:** radioactive iodine (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12976647/full.md

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Source: https://tomesphere.com/paper/PMC12976647