# The long-term domiciliary oxygen therapy experience and needs in patients with chronic obstructive pulmonary disease: a qualitative meta-synthesis

**Authors:** Guannan Ma, Shiyan Yao, Huajuan Shen, Yongze Dong, Luchen Chen, Haixin Song, Yanyu Fang, Xiaoli Shen

PMC · DOI: 10.3389/fresc.2026.1694213 · 2026-02-25

## TL;DR

This study explores the experiences and challenges of COPD patients using long-term home oxygen therapy and identifies their needs.

## Contribution

A qualitative meta-synthesis of COPD patients' experiences with long-term oxygen therapy, highlighting new insights into their challenges and needs.

## Key findings

- Long-term oxygen therapy provides health benefits for COPD patients.
- Patients face significant challenges adapting to long-term oxygen therapy.
- Healthcare professionals should address the adverse effects of oxygen therapy for COPD patients.

## Abstract

To systematically evaluate and integrate the experience and perception of long-term domiciliary oxygen therapy in patients with Chronic Obstructive Pulmonary Disease (COPD). A systematic search of PubMed, Embase, Web of Science, CINAHL, ProQuest, Scopus, Cochrane Library, VIP Database, WanFang, CNKI, and CBM Database for qualitative studies on the experience of long-term domiciliary oxygen therapy in patients with COPD was conducted. The time limit was from the database's inception to 1 August 2025. The qualitative meta-synthesis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 9 papers were included, and 33 outcomes were distilled into nine categories and four integrated outcomes: Health benefits of Long-Term Oxygen Therapy for patients with COPD, the patients with COPD faced many challenges after Long-Term Oxygen Therapy, adaptation to Long-Term Oxygen Therapy in patients with COPD, and the demands of patients with COPD undergoing Long-Term Oxygen Therapy. Although long-term domiciliary oxygen therapy for patients with COPD brings certain health benefits, they also face a series of problems and challenges. In the future, healthcare professionals should pay attention to the experience of long-term domiciliary oxygen therapy for patients with COPD and actively address its adverse effects.

https://www.crd.york.ac.uk/PROSPERO/view/CRD420251086510, PROSPERO CRD420251086510.

## Linked entities

- **Diseases:** Chronic Obstructive Pulmonary Disease (MONDO:0005002), COPD (MONDO:0005002)

## Full-text entities

- **Diseases:** COPD (MESH:D029424)
- **Chemicals:** Oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12976016/full.md

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Source: https://tomesphere.com/paper/PMC12976016