# Effect of milk and dairy intake on cognitive function in older adults: a systematic review and meta-analysis

**Authors:** Yessica Giraldo-Castrillon, Juan Diego Mendoza, Marianne Lopez-Cabrera, Jose P. Lopez-Lopez, Patricio Lopez-Jaramillo

PMC · DOI: 10.3389/fragi.2026.1709281 · 2026-02-25

## TL;DR

This study finds that milk and dairy intake may improve cognitive function in older adults, particularly through randomized trials.

## Contribution

The study provides novel evidence from randomized controlled trials supporting dairy's cognitive benefits in older adults.

## Key findings

- Randomized trials showed significant improvements in global cognition, memory, and processing speed with dairy intake.
- Fermented and fortified dairy products were associated with moderate to high certainty of cognitive benefits.
- Observational studies did not show a significant positive effect of dairy on cognitive function.

## Abstract

Cognitive aging represents a growing challenge for global public health. Nutrition could have a beneficial effect in preserving cognitive function, and dairy products have been proposed as neuroprotective due to their nutrient density and bioactive compounds. In this systematic review and meta-analysis, we evaluated the association between milk and dairy product intake and cognitive function in older adults.

The systematic search was conducted in PubMed, Scopus, LILACS, and Google Scholar through 9 August 2025, including randomized controlled trials (RCT) and observational studies evaluating dairy intake versus low or no intake in adults aged ≥60 years. Meta-analysis were conducted using a random-effects model, and methodological quality was assessed using RoB 2.0 (Risk of Bias), ROBINS-I (Risk Of Bias in Non-randomized Studies), and GRADE (Grading of Recommendations Assessment, Development and Evaluation).

22 studies were included (11 RCT, 11 observational studies; n = 47.100), of which 5 RCT (n = 369) and 5 observational (n = 5.302) studies were analyzed by meta-analysis. RCT revealed significant positive effects on global cognition [Standardized Mean Difference -SMD-) = 0.45; 95%CI: 0.30–0.60], memory, and processing speed. This effect was associated in fermented and fortified products, with moderate to high certainty. In observational studies no positive effect emerged (Odds Ratio [OR] = 0.95 95%CI: 0.89–1.02).

Our findings support the potential of dairy intake as a nutritional strategy to preserve cognitive function in older adults, with implications for clinical practice, public health, and food policy design.

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12975744/full.md

---
Source: https://tomesphere.com/paper/PMC12975744