# Increasing the rigor of body composition and adiposity measurement in multiple sclerosis research

## TL;DR

This paper discusses the importance of using more accurate methods to measure body fat in multiple sclerosis research.

## Contribution

The paper highlights the benefits of using advanced techniques for measuring adiposity in MS studies.

## Key findings

- Current methods like BMI do not accurately assess adipose tissue types or locations.
- More rigorous techniques can provide better insights into health risks related to adiposity in MS patients.

## Abstract

Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease that affects nearly 1 million adults in the United States, and over half of this population also has overweight or obesity. The compounding effect of multiple disease states could increase disease progression and worsen MS symptoms. MS researchers frequently use anthropometric measures, such as BMI and waist circumference, as an assessment of obesity. However, these measurements do not provide a direct assessment of types or location of adipose tissue, which may provide a more accurate assessment of adiposity-related health risk. The main objectives of this mini review are to provide a brief overview of current adiposity measurement techniques in MS research and highlight potential benefits of using more rigorous indirect and direct techniques to measure total, regional, and specific fat depots.