Multi-axial strain mapping to characterise structure and material properties of the human hip capsule
Kabelan J. Karunaseelan, K.C. Geoffrey Ng, Sarah K. Muirhead-Allwood, Richard J. van Arkel, Jonathan R. T. Jeffers, Alessandra Aldieri, Alessandra Aldieri, Alessandra Aldieri
TL;DR
This study introduces a method to map collagen structures in the human hip capsule using strain measurements, revealing tissue architecture and mechanical properties.
Contribution
A practical method combining biaxial testing and 2D DIC to quantify collagen networks and mechanical properties in whole tissues.
Findings
Collagen bundles in the hip capsule show lower strain compared to the surrounding matrix under biaxial loading.
Seven ligamentous regions were identified and matched to anatomical descriptions using strain patterns.
Local mechanical properties like tangent modulus were extracted across the entire tissue in a single test.
Abstract
The biological composition and spatial arrangement of the tissue’s constituents are directly related to its condition and function. Conventional inspection techniques such as optical microscopy and exogenous staining have limited ability to capture the heterogeneity and anisotropy of biological tissues. Here, we apply a commercial 2D digital image correlation (DIC) system integrated with a biaxial testing machine to quantitatively characterise the fibrous structure of biological materials. The approach applies a homogeneous biaxial stress field across the tissue and uses optical measurement of the resulting strain field to identify load-bearing collagen architecture. Under this loading condition, collagen bundles deform less than the surrounding matrix, so low-strain bands and their principal directions indicate ligament locations and orientations. The method was validated using an…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14
Figure 15
Figure 16
Figure 17
Figure 18
Figure 19
Figure 20
Figure 21
Figure 22
Figure 23
Figure 24
Figure 25
Figure 26
Figure 27
Figure 28
Figure 29
Figure 30
Figure 31
Figure 32
Figure 33Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsElasticity and Material Modeling · Bone health and osteoporosis research · Collagen: Extraction and Characterization