# Validity of the Turkish version of the Oral Frailty Index-8 and its relationship with frailty, malnutrition, and sarcopenia in older adults

**Authors:** Süleyman Emre KOÇYİĞİT, Bilal KATİPOĞLU, Yılmaz ÖNAL, Kübra BAHAR BAYKAN, İlknur ŞEKER KAYA, Fatma Sena DOST, Özge DOKUZLAR, Esra ATEŞ BULUT, Ali Ekrem AYDIN, Derya KAYA, Ahmet Turan IŞIK

PMC · DOI: 10.55730/1300-0144.6137 · 2025-11-14

## TL;DR

This study validates the Turkish version of the Oral Frailty Index-8 and shows it can help identify oral frailty and related health issues in older adults.

## Contribution

The study provides the first Turkish validation of the OFI-8 and establishes a cut-off score for identifying oral frailty.

## Key findings

- The OFI-8 showed good test-retest reliability (ICC 0.961) and internal consistency (Cronbach’s α 0.728).
- A cut-off score of ≥5 on the OFI-8 predicted physical frailty, malnutrition, and probable sarcopenia with moderate accuracy.
- Probable sarcopenia, physical frailty, polypharmacy, malnutrition, and falls were independently associated with oral frailty.

## Abstract

The Oral Frailty Index-8 (OFI-8) is a reliable screening for oral frailty. In our study, while presenting the Turkish reliability and validity study of the OFI-8, we also aimed to establish a cut-off value for oral frailty in Turkish population.

Patients who presented to the outpatient clinic between January 2024 and January 2025 were evaluated. The test’s internal consistency and test–retest reliability were assessed. Divergent validity was evaluated using frailty scores, muscle strength, and nutritional status. A receiver operating characteristic (ROC) curve was generated to determine the optimal cut-off values for identifying frailty, malnutrition, and probable sarcopenia. Oral frailty status was then analyzed in relation to demographic characteristics, comorbidities, and geriatric syndromes. Regression analyses were performed to adjust for confounding factors.

In 162 patients, internal consistency was quantified with a Cronbach’s α of 0.728, and test–retest reliability was quantified with an intraclass correlation coefficient (ICC) of 0.961. Construct validity was supported by exploratory factor analysis, and divergent validity was confirmed through significant correlations with frailty, muscle strength, and nutritional status. A cut-off score of ≥ 5 on the OFI-8 was identified for predicting physical frailty, malnutrition, and probable sarcopenia: for frailty status, the area under the curve (AUC) was 0.75 [95% confidence interval (CI) 0.67–0.82; p < 0.001], sensitivity 0.85 and specificity 0.56; for probable sarcopenia, AUC was 0.68 (95% CI 0.60–0.77; p < 0.001), sensitivity 0.71 and specificity 0.52; and for nutritional status, AUC was 0.76 (95% CI 0.68–0.84; p < 0.001), sensitivity 0.86 and specificity 0.55. Independent of confounding factors, probable sarcopenia, physical frailty, polypharmacy, malnutrition, and falls remained significantly associated with oral frailty (OFI-8 score ≥5).

OFI-8 demonstrates good validity and reliability for detecting oral frailty in Turkish older adults, supporting early diagnosis and intervention to address better related conditions such as frailty, probable sarcopenia, and malnutrition.

## Linked entities

- **Diseases:** malnutrition (MONDO:0006873)

## Full-text entities

- **Diseases:** falls (MESH:C537863), Oral Frailty (MESH:D000073496), sarcopenia (MESH:D055948), malnutrition (MESH:D044342)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12974279/full.md

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Source: https://tomesphere.com/paper/PMC12974279