# Updated peer review of the pesticide risk assessment of the active substance clodinafop (variant evaluated clodinafop‐propargyl)

**Authors:** Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza

PMC · DOI: 10.2903/j.efsa.2026.9871 · 2026-03-10

## TL;DR

This paper summarizes the updated peer review of the pesticide clodinafop-propargyl, focusing on its risk assessment and regulatory concerns.

## Contribution

The paper provides updated conclusions on the risk assessment and identifies missing information and concerns for clodinafop-propargyl.

## Key findings

- The peer review evaluated the use of clodinafop-propargyl as a herbicide on wheat, rye, and triticale.
- Concerns were identified, and the acceptable operator exposure level was reconsidered.
- The assessment was updated to address endocrine-disrupting properties following a new mandate.

## Abstract

The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Greece, and co‐rapporteur Member State, Germany, for the pesticide active substance clodinafop‐propargyl are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012. The conclusions were reached on the basis of the evaluation of the representative uses of clodinafop‐propargyl as a herbicide on wheat, rye and triticale. The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified. The European Commission mandated EFSA to reconsider the acceptable operator exposure level (AOEL) setting and to update the non‐dietary exposure assessment if needed. In addition, the conclusions were updated with regard to the endocrine‐disrupting properties following a mandate received from the European Commission in November 2020.

## Linked entities

- **Chemicals:** clodinafop-propargyl (PubChem CID 92431)

## Full-text entities

- **Chemicals:** clodinafop (MESH:C400760), clodinafop-propargyl (MESH:C561036)
- **Species:** x Triticosecale (triticale, genus) [taxon 49317]

## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12972835/full.md

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Source: https://tomesphere.com/paper/PMC12972835