# The evolving role of endoscopic ultrasound from diagnosis to therapy in hepatic vascular interventions

**Authors:** Shixue Xu, Jitong Jiang, Jintao Guo, Sheng Wang, Nan Ge, Rongmin Xu, Fan Yang

PMC · DOI: 10.3389/fmed.2026.1742411 · Frontiers in Medicine · 2026-02-24

## TL;DR

Endoscopic ultrasound is transforming from a diagnostic tool to a key method for treating liver vascular conditions.

## Contribution

The paper highlights novel therapeutic applications of EUS in hepatic vascular interventions.

## Key findings

- EUS-guided portal pressure gradient measurement is emerging as a new standard for assessing portal hypertension.
- EUS enables precise embolization of gastric varices and shunts, improving treatment accuracy.
- EUS-guided intrahepatic portosystemic shunts are being developed as a new therapeutic approach.

## Abstract

Endohepatology, the integration of advanced endoscopy into hepatology, is rapidly evolving beyond standard diagnostics. This review focuses on its burgeoning vascular applications, particularly through endoscopic ultrasound (EUS). EUS-guided portal pressure gradient measurement (EUS-PPG) is establishing a new paradigm for direct portal hypertension assessment. Therapeutically, EUS enables precise vascular interventions such as coil and glue embolization for gastric varices and spontaneous portosystemic shunts, moving beyond blind techniques. Pioneering, bench-to-bedside procedures like the creation of EUS-guided intrahepatic portosystemic shunts (EUS-IPS) represent the next frontier. While technical complexity remains, EUS is a transformative platform within endohepatology. This article explores these cutting-edge applications and prognosticates future techniques set to redefine the management of complex hepatobiliary and vascular diseases.

## Linked entities

- **Diseases:** portal hypertension (MONDO:0005080)

## Full-text entities

- **Diseases:** hepatobiliary and vascular diseases (MESH:D004066), portal hypertension (MESH:D006975), gastric varices (MESH:D004932)

## Full text

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## References

64 references — full list in the complete paper: https://tomesphere.com/paper/PMC12971473/full.md

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Source: https://tomesphere.com/paper/PMC12971473