# Can a Rule-Based Expert System Diagnose Nasal Obstruction from Nasoendoscopy Videos?

**Authors:** Annakan Navaratnam, Nonpawith Phoommanee, Vikas Acharya, Alfonso Luca Pendolino, Terence S. Leung, Peter J. Andrews

PMC · DOI: 10.1055/a-2656-6413 · Facial Plastic Surgery · 2025-07-28

## TL;DR

A rule-based expert system was tested to diagnose nasal obstruction causes and showed similar performance to ENT specialists, especially for chronic rhinosinusitis with nasal polyps.

## Contribution

A rule-based expert system was developed and validated to replicate ENT decision-making for nasal obstruction diagnosis.

## Key findings

- RB-ES showed no significant sensitivity differences from ENT specialists for nasal obstruction diagnoses.
- Sensitivity was highest for chronic rhinosinusitis with nasal polyps (CRSwNP).
- Specificity remained high overall across all conditions evaluated.

## Abstract

Nasal obstruction has multiple causes requiring specialist endoscopy for diagnosis. A rule-based expert system (RB-ES), which applies five “if–then” rules based on nasal features, may help replicate ENT decision-making in settings with limited access.

This study evaluated RB-ES in diagnosing allergic rhinitis, chronic rhinosinusitis with (CRSwNP) and without (CRSsNP) nasal polyps, and deviated nasal septum. Primary outcomes were sensitivity and specificity; the secondary outcome was agreement with ENT specialists.

Prospective cohort study.

Seventy-one participants (65 patients, 6 controls) underwent pre- and postdecongestion endoscopy. Four ENT specialists provided diagnoses. RB-ES performance was compared against confirmed clinical diagnoses.

RB-ES showed no detectable significant sensitivity differences from ENT specialists (all
p
 > 0.05). Sensitivity was highest for CRSwNP; specificity remained high overall.

RB-ES matched specialist performance in CRSwNP diagnosis. Dataset expansion and artificial intelligence integration are recommended for further validation.

II.

## Linked entities

- **Diseases:** allergic rhinitis (MONDO:0011786)

## Full-text entities

- **Diseases:** Nasal obstruction (MESH:D015508), DNS (MESH:D061270), chronic rhinosinusitis (MESH:D000092562), nasal polyps (MESH:D009298), AR (MESH:D065631)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12971217/full.md

## References

38 references — full list in the complete paper: https://tomesphere.com/paper/PMC12971217/full.md

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Source: https://tomesphere.com/paper/PMC12971217