Expression of Concern: The MAPK Pathway Signals Telomerase Modulation in Response to Isothiocyanate-Induced DNA Damage of Human Liver Cancer Cells

Abstract

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Following the publication of this article [1], concerns were raised with results presented in Figs 2 and 3. Specifically,

The corresponding author stated that in order to allow direct comparability of the respective target protein signals with the corresponding β-actin loading control, β-actin loading controls were shown more than once in cases where the same membrane was used for the detection of different target proteins. They also stated that, in Figure 5D of [3], the labeling of the Huh7 and Hep3B samples was inadvertently interchanged. The corresponding author stated that the original raw data for [1] are no longer available.

In light of the above concerns which cannot be fully resolved in the absence of the underlying data, the PLOS One Editors issue this Expression of Concern.