# Artificial intelligence–Driven detection and decision support system for precision management of maize downy mildew

**Authors:** Jadesha G, Anurag Dhole, Deepak D, C Anilkumar, C Anilkumar, C Anilkumar

PMC · DOI: 10.1371/journal.pone.0343517 · PLOS One · 2026-03-09

## TL;DR

This paper presents an AI system that detects maize downy mildew with high accuracy and provides farm advice to improve crop yield and profitability.

## Contribution

A web-based AI system for detecting maize downy mildew and offering precision management solutions is developed and validated in field trials.

## Key findings

- VGG16 achieved 97% accuracy in classifying maize leaves as healthy or infected.
- Field trials showed a significant reduction in disease severity and increased grain yield with AI-guided fungicide use.
- The web-based application improved economic returns with a B:C ratio of 3.36–3.57.

## Abstract

Artificial intelligence (AI) enables rapid and precise plant disease detection, offering transformative potential for crop protection. Maize downy mildew (MDM), a destructive disease, causes substantial yield losses, making early detection critical. In this study, we evaluated the performance of thirteen machine-learning (ML) and deep-learning (DL) algorithms for classifying healthy and infected maize leaves using a curated field dataset. Model performance was assessed using multiple metrics, including accuracy, precision, recall, F1-score, and AUC-ROC. Among the tested models, VGG16 achieved the highest performance, with 97% accuracy, 0.98 precision, 0.95 recall, 0.97 F1-score, and an AUC-ROC of 0.99. Training and validation curves indicated minimal overfitting, demonstrating robust generalization. Feature visualization using t-SNE revealed clear separability between healthy and diseased samples, while Grad-CAM analysis confirmed that VGG16 focused on biologically relevant symptomatic regions, such as chlorotic streaks and leaf discoloration. Confusion matrix analysis further validated near-perfect classification, with very few misclassifications. Furthermore, we developed a web-based application (https://maize-mdm.streamlit.app/) that not only classifies MDM but also provides farm-level advisory measures. Two-year field trials of DSS-guided fungicide applications effectively suppressed MDM, reducing disease severity (PDI 3.20–5.20; PROC 93−96%), increasing grain yield (75.6–80.2 q/ha; PIOC 195−289%), and improving economic returns (B:C ratio 3.36–3.57) compared to untreated controls. Overall, this study demonstrates that AI-driven models, integrated with web-based decision support, provide accurate, interpretable, and actionable solutions for precision management of maize diseases, contributing to improved yield, profitability, and sustainable agricultural practices.

## Full-text entities

- **Diseases:** MDM Disease (MESH:D004194), AI (MESH:C538142), leaf discoloration (MESH:D014075), ACADEMIC EDITOR (MESH:D007859), plant disease (MESH:D010939), leaf stunting (MESH:D006130), MDM infection (MESH:D007239)
- **Chemicals:** triazoles (MESH:D014230), DSS (-), Difenoconazole (MESH:C115058), Mancozeb (MESH:C013099), CB (MESH:C063451), strobilurins (MESH:D000073739), ethanol (MESH:D000431), Metalaxyl (MESH:C028175), starch (MESH:D013213), Azoxystrobin (MESH:C087670)
- **Species:** Peronosclerospora (genus) [taxon 230838], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Zea mays (maize, species) [taxon 4577]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12970884/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC12970884/full.md

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Source: https://tomesphere.com/paper/PMC12970884