# First person – Tabea Soelter and Emma Jones

## TL;DR

This paper presents an interview with Tabea Soelter and Emma Jones, who studied alternative splicing in a mouse model of Schinzel–Giedion syndrome.

## Contribution

The study explores cell-type-specific alternative splicing in brain and kidney tissues of a mouse model for Schinzel–Giedion syndrome.

## Key findings

- The research identifies cell-type-specific alternative splicing patterns in brain and kidney tissues.
- Findings contribute to understanding the molecular mechanisms of Schinzel–Giedion syndrome.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Tabea Soelter and Emma Jones are co-first authors on ‘
Cell-type-specific alternative splicing in the brain and kidney of a Setbp1S858R Schinzel–Giedion syndrome mouse’, published in DMM. Tabea is a computational biologist in the lab of Brittany Lasseigne at The University of Alabama at Birmingham, Birmingham, AL, USA, using transcriptomics and bioinformatics to uncover the mechanisms underlying age-associated diseases, specifically those with a neurodegenerative phenotype. Emma conducted the research described in this article while a PhD student in Brittany Lasseigne's lab at The University of Alabama at Birmingham. She is now a postdoc in the lab of Joseph Dougherty at Washington University in St Louis, St Louis, MO, USA, using transcriptomics to understand the mechanisms underlying neurodevelopmental and psychiatric disorders.