# A primary healthcare approach to children with fever

**Authors:** Indiran Govender, Henry I. Okonta

PMC · DOI: 10.4102/safp.v68i1.6199 · South African Family Practice · 2026-02-23

## TL;DR

This paper provides a guideline for primary healthcare workers in South Africa on managing children with fever to ensure serious illnesses are not missed.

## Contribution

The paper offers a practical guideline for primary care practitioners to assess and manage febrile children effectively.

## Key findings

- Many childhood fevers are self-limiting but require careful evaluation.
- Primary healthcare practitioners need to identify and exclude serious diseases in febrile children.
- The guideline should be used alongside specific disease management protocols.

## Abstract

A child with fever presenting with concerned caregivers is a common occurrence in primary healthcare in South Africa. Many fevers are self-limiting. However, serious and possibly fatal diseases must be excluded before discharging the child. This article is a guideline for primary care practitioners, which needs to be read in conjunction with the management guidelines for specific diseases.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** TB (MESH:D014376), sickle cell anaemia (MESH:D000755), myalgia (MESH:D063806), Leukaemia (MESH:D015458), Kawasaki disease (MESH:D009080), inflammatory bowel diseases (MESH:D015212), lymphoma (MESH:D008223), SBI (MESH:D001424), measles (MESH:D008457), infectious disorders (MESH:D003141), brucellosis (MESH:D002006), pertussis (MESH:D014917), yellow fever (MESH:D015004), heatstroke (MESH:D018883), typhoid fever (MESH:D014435), hyperbilirubinemia (MESH:D006932), malaria (MESH:D008288), HIV (MESH:D015658), brain damage (MESH:D001925), viral diseases (MESH:D014777), death (MESH:D003643), sore throat (MESH:D010612), factitious disorder (MESH:D005162), cramps (MESH:D009120), congenital heart disease (MESH:D006330), juvenile idiopathic arthritis (MESH:D001171), urinary tract infections (MESH:D014552), dehydration (MESH:D003681), herpes simplex (MESH:D006561), Scarlet fever (MESH:D012541), Neonatal or infant infections (MESH:D007239), pneumonia (MESH:D011014), diarrhoea (MESH:D003967), familial dysautonomia (MESH:D004402), cytomegalovirus (MESH:D003586), dysautonomia (MESH:D054969), tachycardia (MESH:D013610), Febrile (MESH:D000071072), dengue fever (MESH:D003715), autoimmune conditions (MESH:D001327), AIDS (MESH:D000163), travel (MESH:D000076082), vomiting (MESH:D014839), bradycardia (MESH:D001919), systemic lupus erythematosus (MESH:D008180), otitis media (MESH:D010033), neuroblastoma (MESH:D009447), Food-borne- and/or water-borne (MESH:D005517), Chronic fever (MESH:D005334), seizures (MESH:D012640), skin conditions (MESH:D012871), pain (MESH:D010146), headache (MESH:D006261), inflammatory (MESH:D007249), respiratory or gastrointestinal infections (MESH:D012141), bacteraemia (MESH:C531821), anxiety (MESH:D001007), acute rheumatic fever (MESH:D012213), meningitis (MESH:D008580), DM (MESH:D009223)
- **Chemicals:** Ampicillin (MESH:D000667), creatinine (MESH:D003404), cefotaxime (MESH:D002439), urea (MESH:D014508), ceftriaxone (MESH:D002443), PGE2 (MESH:D015232), gentamycin (MESH:D005839), oxygen (MESH:D010100), Paracetamol (MESH:D000082), ibuprofen (MESH:D007052)
- **Species:** Human immunodeficiency virus (species) [taxon 12721], Listeria monocytogenes (species) [taxon 1639], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685], Streptococcus pneumoniae (species) [taxon 1313], Human immunodeficiency virus 1 (no rank) [taxon 11676], Escherichia coli (E. coli, species) [taxon 562]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12969632/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969632/full.md

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Source: https://tomesphere.com/paper/PMC12969632