# Self-expandable valve-in-valve transcatheter aortic valve implantation for a failed sutureless Perceval bioprosthesis: a case report

**Authors:** Strahil K Vasilev, Ivo S Petrov, Zoran I Stankov, Dayana K Emanuilova

PMC · DOI: 10.1093/ehjcr/ytag095 · European Heart Journal. Case Reports · 2026-02-04

## TL;DR

A 78-year-old woman with a failed Perceval heart valve was successfully treated with a less invasive valve-in-valve procedure.

## Contribution

Demonstrates successful use of self-expandable valve-in-valve TAVI for a failed sutureless Perceval bioprosthesis.

## Key findings

- ViV-TAVI is a viable option for patients with failed sutureless Perceval valves and high surgical risk.
- Computed tomography-based planning is crucial for successful self-expandable ViV-TAVI.
- Fluoroscopic visualization of the Perceval inflow ring aided procedural success.

## Abstract

Early structural degeneration of sutureless Perceval bioprostheses is uncommon but may result in severe haemodynamic compromise and heart failure. Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) represents a less invasive therapeutic option in high-risk patients.

A 78-year-old woman presented with progressive dyspnoea and lower-extremity oedema 3 years after surgical aortic valve replacement with a Perceval bioprosthesis. Transthoracic echocardiography revealed severe mixed prosthetic valve dysfunction with markedly elevated transvalvular gradients. Owing to prohibitive surgical risk, comprehensive preprocedural planning with echocardiography and multidetector computed tomography was performed to assess annular dimensions and coronary anatomy. A self-expandable ViV-TAVI was successfully performed, guided by fluoroscopic visualization of the Perceval inflow ring.

This case highlights the importance of understanding sutureless valve geometry and meticulous computed tomography–based planning when performing ViV-TAVI with a self-expandable transcatheter valve.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** mitral regurgitation (MESH:D008944), pulmonary hypertension (MESH:D006976), Type 2 diabetes mellitus (MESH:D003924), pleural effusion (MESH:D010996), heart failure (MESH:D006333), tricuspid regurgitation (MESH:D014262), anaemia (MESH:D000743), drug allergies (MESH:D004342), heart disease (MESH:D006331), lower-extremity oedema (MESH:C536897), shortness of breath (MESH:D004417), valve degeneration (MESH:D006349), paravalvular leak (MESH:D019559), hypertension (MESH:D006973), coronary obstruction (MESH:D000088442)
- **Chemicals:** Evolut R (-), nitinol (MESH:C013616)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12969585/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969585/full.md

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Source: https://tomesphere.com/paper/PMC12969585