# High prevalence of endometriosis in women with chronic pelvic pain and confirmed pelvic varicosities: a multiparametric MRI study

**Authors:** Mira Zlotnik, Marcos de Lorenzo Messina, Thiago Dieb Ristum Vieira, Vinicius Bertoldi, Andrei Skromov de Albuquerque, Pedro Puech-Leão, Edmund Chada Baracat

PMC · DOI: 10.1016/j.clinsp.2026.100895 · Clinics · 2026-03-03

## TL;DR

A study found that over 60% of women with chronic pelvic pain and pelvic varicosities also had endometriosis, using MRI to detect both conditions non-invasively.

## Contribution

The study reveals a high prevalence of endometriosis in women with pelvic varicosities and demonstrates the effectiveness of multiparametric MRI for integrated diagnosis.

## Key findings

- Endometriosis was found in 61.5% of women with chronic pelvic pain and pelvic varicosities.
- Multiparametric MRI can detect both vascular and gynecological abnormalities in a single session.
- Integrated imaging may improve the diagnostic workup for chronic pelvic pain.

## Abstract

•Endometriosis was found in 61.5 % of women with chronic pelvic pain and confirmed pelvic varicosities.•Multiparametric MRI allows non-invasive, simultaneous detection of vascular and gynecological abnormalities.•Integrated imaging may improve diagnostic workup in women with chronic pelvic pain.

Endometriosis was found in 61.5 % of women with chronic pelvic pain and confirmed pelvic varicosities.

Multiparametric MRI allows non-invasive, simultaneous detection of vascular and gynecological abnormalities.

Integrated imaging may improve diagnostic workup in women with chronic pelvic pain.

Chronic Pelvic Pain (CPP) presents significant diagnostic challenges, often involving multiple pathologies, including endometriosis and pelvic venous disorders. This study examined the prevalence of endometriosis among women with confirmed pelvic varicosities.

The authors performed a retrospective analysis of 52 women with CPP and pelvic varicosities who underwent multiparametric magnetic resonance venography between January 2019 and December 2023. All images were reviewed by a single experienced radiologist, blinded to clinical data and vascular findings, to identify radiological signs of endometriosis.

Among the 52 women, 32 exhibited radiological findings consistent with endometriosis, corresponding to a prevalence of 61.5% (95% CI: 47.0%–74.5%).

This study demonstrates a high prevalence of endometriosis among women with pelvic varicosities. Multiparametric MRI proved effective as a non-invasive diagnostic modality capable of identifying both vascular and gynecologic abnormalities in a single session, supporting integrated assessment approaches for women with CPP. Limitations include the retrospective design and the lack of histological confirmation of endometriosis.

## Linked entities

- **Diseases:** endometriosis (MONDO:0005133)

## Full-text entities

- **Genes:** IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** vascular (MESH:D057772), infertility (MESH:D007246), dyspareunia (MESH:D004414), Pelvic Pain (MESH:D017699), dysmenorrhea (MESH:D004412), CPP (MESH:D011472), chronic (MESH:D002908), dyschezia (MESH:D003248), , bowel, pelvic floor, myofascial, or gynecological dysfunction (MESH:D059952), gynecological abnormalities (MESH:D005831), PeVD (MESH:D034161), pelvic venous insufficiency (MESH:D014689), vulvar or lower limb varicosities (MESH:D014845), Endometriosis (MESH:D004715), pain (MESH:D010146), inflammatory (MESH:D007249), Pelvic varicosities (MESH:D014647), venous congestion (MESH:D006940)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12969381/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969381/full.md

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Source: https://tomesphere.com/paper/PMC12969381