# Transfemoral Transcatheter Aortic Valve Implantation for Severe Aortic Stenosis in a Patient With Prior Tendyne Transcatheter Mitral Valve Replacement: Expanding the Boundaries of Transcatheter Valve Therapy

**Authors:** Rajan Rehan, Ben McDonough, Bernard Prendergast, Simon Redwood

PMC · DOI: 10.1016/j.shj.2026.100802 · Structural Heart · 2026-01-23

## TL;DR

This paper shows that aortic valve implantation can be safely done in patients who previously had a Tendyne mitral valve replacement.

## Contribution

It introduces a safe approach for transcatheter aortic valve implantation after prior Tendyne mitral valve replacement.

## Key findings

- Transfemoral transcatheter aortic valve implantation is feasible in patients with prior Tendyne mitral valve replacement.
- Preprocedural CT planning helps assess risks of left ventricular outflow tract obstruction and device interaction.
- Self-expanding aortic valves may reduce device interaction risks in complex anatomical cases.

## Abstract

•Transfemoral transcatheter aortic valve implantation can be safely performed in patients with prior Tendyne transcatheter mitral valve replacement.•Careful preprocedural computed tomography planning allows assessment of left ventricular outflow tract obstruction risk and spatial interaction between the Tendyne frame and the aortic annulus.•Use of a self-expanding transcatheter aortic valve may minimize the risk of device interaction in this complex anatomical setting.

Transfemoral transcatheter aortic valve implantation can be safely performed in patients with prior Tendyne transcatheter mitral valve replacement.

Careful preprocedural computed tomography planning allows assessment of left ventricular outflow tract obstruction risk and spatial interaction between the Tendyne frame and the aortic annulus.

Use of a self-expanding transcatheter aortic valve may minimize the risk of device interaction in this complex anatomical setting.

## Linked entities

- **Diseases:** aortic stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** congestive cardiac failure (MESH:D006333), dilated left ventricle (MESH:D020257), systolic dysfunction (MESH:D006331), Aortic Stenosis (MESH:D001024), mitral regurgitation (MESH:D008944), multivalvular disease (MESH:D004194), LVOT obstruction (MESH:D000092242), calcification (MESH:D002114)
- **Chemicals:** Tendyne (-), nitinol (MESH:C013616)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12969293/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969293/full.md

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Source: https://tomesphere.com/paper/PMC12969293