# Dataset of chloroplast DNA sequences, ndhC–trnV, rpoA, trnK–matK, and trnK–rps16 regions of Platycodon grandiflorus (Jacq.) A.DC. from Vietnam

**Authors:** Dung Manh Ngo, Luong Trong Vu, Hung Duc Nguyen, Thuy Thi Thu Vu, Mau Hoang Chu

PMC · DOI: 10.1016/j.dib.2026.112627 · Data in Brief · 2026-02-25

## TL;DR

This paper provides DNA sequences from four chloroplast regions of the medicinal plant Platycodon grandiflorus to help accurately identify it and avoid misidentification.

## Contribution

The study introduces four chloroplast DNA regions as potential DNA barcodes for reliable identification of Platycodon grandiflorus.

## Key findings

- Phylogenetic analysis shows P. grandiflorus clusters within the Campanulaceae family with high bootstrap support.
- Four chloroplast regions (ndhC–trnV, rpoA, trnK–matK, trnK–rps16) are proposed as effective DNA barcodes for species identification.
- The dataset supports accurate identification and differentiation of P. grandiflorus from related species.

## Abstract

Platycodon grandiflorus (Jacq.) A.DC., a member of the Campanulaceae family, is a well-known medicinal herb traditionally used to relieve coughs, promote expectoration, reduce inflammation, and protect the respiratory system. In recent years, numerous commercial products containing Platycodon extracts have been introduced to the market. However, during processing and distribution, the morphological and anatomical features of the raw material are often lost or altered, increasing the risk of misidentification or adulteration with morphologically similar species, thereby compromising product quality and therapeutic efficacy. Therefore, the application of DNA barcode markers is essential for accurate species identification and quality control of raw materials. This study presents a dataset of P. grandiflorus samples collected from natural populations and analyzes four chloroplast DNA regions (ndhC-trnV, rpoA, trnK-matK, and trnK-rps16) to support species identification. Phylogenetic analysis based on these sequences revealed that P. grandiflorus is closely related to, and clusters within, the Campanulaceae family, with high bootstrap support values (96–100%). These four chloroplast regions are proposed as potential DNA barcodes for the reliable identification and differentiation of P. grandiflorus from related species.

## Linked entities

- **Genes:** ndhC (NADH dehydrogenase subunit 3) [NCBI Gene 800470], TRNV (tRNA-Val) [NCBI Gene 4577], rpoA (RNA polymerase alpha subunit) [NCBI Gene 800197], MATK (megakaryocyte-associated tyrosine kinase) [NCBI Gene 4145], RPS16 (ribosomal protein S16) [NCBI Gene 6217]
- **Species:** Platycodon grandiflorus (taxon 94286), Campanulaceae (taxon 4381)

## Full-text entities

- **Diseases:** cough (MESH:D003371), inflammation (MESH:D007249), respiratory disorders (MESH:D012131)
- **Chemicals:** CTAB (MESH:D000077286), agarose (MESH:D012685), water (MESH:D014867)
- **Species:** Homo sapiens (human, species) [taxon 9606], Platycodon (genus) [taxon 94285], Platycodon grandiflorus (balloon flower, species) [taxon 94286]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12969150/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969150/full.md

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Source: https://tomesphere.com/paper/PMC12969150