# Intravenous immunoglobulin for the treatment of morphea in pediatric patients: A case series

**Authors:** Milica Milakovic, Ronald M. Laxer, Elena Pope, Cathryn Sibbald

PMC · DOI: 10.1016/j.jdcr.2025.05.049 · JAAD Case Reports · 2025-07-12

## Full-text entities

- **Genes:** CXCL9 (C-X-C motif chemokine ligand 9) [NCBI Gene 4283] {aka CMK, Humig, MIG, SCYB9, crg-10}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, IFNG (interferon gamma) [NCBI Gene 3458] {aka IFG, IFI, IMD69}
- **Diseases:** edema (MESH:D004487), atrophy (MESH:D001284), inflammatory skin condition (MESH:D012871), pain (MESH:D010146), fasciitis (MESH:D005208), headache (MESH:D006261), inflammation (MESH:D007249), contractures (MESH:D003286), vomiting (MESH:D014839), systemic lupus erythematosus (MESH:D008180), pruritus (MESH:D011537), diarrhea (MESH:D003967), myositis (MESH:D009220), skin induration (MESH:D010411), xerotic (MESH:C536156), nausea (MESH:D009325), impetigo (MESH:D007169), aseptic meningitis (MESH:D008582), autoimmune dermatologic conditions (MESH:D000168), gastrointestinal side (MESH:D005767), Localized Scleroderma (MESH:D012594), urticarial eruption (MESH:D003875), granuloma annulare (MESH:D016460), hypopigmented macules (MESH:C537836), arthritis (MESH:D001168), erythema (MESH:D004890), eosinophilic fasciitis (MESH:C562487), tenosynovitis (MESH:D013717)
- **Chemicals:** tofacitinib (MESH:C479163), hydrocortisone (MESH:D006854), mupirocin (MESH:D016712), acetaminophen (MESH:D000082), tocilizumab (MESH:C502936), MMF (MESH:D009173), calcipotriol (MESH:C055085), rupatadine (MESH:C103639), methylprednisolone (MESH:D008775), methotrexate (MESH:D008727), betamethasone dipropionate (MESH:C011175), PGA-A (-), prednisone (MESH:D011241), steroid (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12969031/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12969031/full.md

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Source: https://tomesphere.com/paper/PMC12969031