# A Randomized Exploratory Study Comparing the Success Rate of Ultrasound Guided Central Venous Catheterization With a Curved Tip Needle Versus a Conventional Straight Needle in Adult Patients

**Authors:** Mridul Dhar, Vijay Adabala, Anirban B Adhikary, Pulkit Johar, Osharani Rathod, Azhar Khan

PMC · DOI: 10.7759/cureus.103137 · Cureus · 2026-02-06

## TL;DR

This study compares curved and straight needles for central venous catheterization in adults and finds similar success rates and safety.

## Contribution

The study explores a curved-tip needle designed for small veins in adults, showing comparable performance to conventional needles.

## Key findings

- First pass success rate was 95% for both curved and straight needles.
- No complications were observed in either group.
- Needle visualization under ultrasound was similar between the two groups.

## Abstract

Introduction: Central venous catheter insertion is routinely performed in adults with high success rates under ultrasound guidance, but guidewire advancement can be difficult in patients with small-caliber veins, particularly in neonates and infants. This randomized exploratory study in adult patients evaluates whether a curved-tip needle, conceptually designed for use in smaller veins, performs at least as well as a standard needle in internal jugular vein (IJV) cannulation.

Methods: In this prospective, randomized exploratory study, adult patients requiring ultrasound-guided IJV cannulation for any indication were included. Forty participants were randomized into two groups: the curved group (CG), using a curved tip needle (10°), and the standard group (SG), using a conventional straight needle. The primary outcome was the first pass success rate. Secondary objectives were overall success rate, number of attempts, needle visualization, and complications.

Results: Results were similar in both the CG and SG in terms of first pass success rate (95%), overall success rate (100%), and number of attempts. Needle visualization under ultrasound was similar in both groups. No complications were noted in either group.

Conclusion: Use of a curved tip needle for IJV catheterization in adults showed similar success rates and needle visualization compared with a conventional straight needle, with no added complications. Further research may explore its utility in non-operative settings, in smaller caliber veins, and at alternative central venous sites.

## Full-text entities

- **Diseases:** infection (MESH:D007239), coagulopathy (MESH:D001778), thrombus (MESH:D013927), sepsis (MESH:D018805), complication (MESH:D008107)
- **Chemicals:** lignocaine (MESH:D008012), GA (MESH:D005708), adrenaline (MESH:D004837)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12968585/full.md

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Source: https://tomesphere.com/paper/PMC12968585