# Mini-review on human-centered assurance in robot-assisted orthopedics and neurosurgery

**Authors:** Sue Min Cho, Xinrui Zou, Laura Fleig, Mathias Unberath

PMC · DOI: 10.3389/frobt.2026.1755883 · Frontiers in Robotics and AI · 2026-02-23

## TL;DR

This mini-review discusses how surgeons can maintain control and ensure safety as robotic systems become more autonomous in orthopedic and neurosurgical procedures.

## Contribution

The paper introduces a human-centered assurance framework for robot-assisted surgery, emphasizing oversight and responsibility.

## Key findings

- Human operators need effective assurance mechanisms as surgical robots gain more autonomy.
- The Sense-Think-Act framework highlights spatial intelligence, cognitive assistance, and physical operation as key areas.
- Research is needed to develop scalable assurance systems that maintain human control and responsibility.

## Abstract

As artificial intelligence (AI) drives the development of next-generation robotic platforms and navigation systems that operate with increasing levels of autonomy in orthopedic and neurosurgical procedures, the methods by which human operators verify and validate these systems’ operations become critically important. While significant effort has been spent on advancing technological capabilities and autonomy, comparatively little thought has been put into understanding how surgeons may effectively maintain oversight and assurance of these complex systems–despite retaining full legal and ethical responsibility for surgical outcomes. This mini-review synthesizes assurance mechanisms following the Sense-Think-Act framework: spatial intelligence (navigation and registration), cognitive assistance (AI-driven planning and adaptation), and physical operation (robot motion and force interaction). We highlight human-centered assurance as an opportunity to enable safe adoption of increasingly autonomous surgical systems. Finally, we outline essential research directions for developing assurance frameworks that scale with increasing autonomy while maintaining human responsibility and control in orthopedic and neurosurgical procedures.

## Full-text entities

- **Diseases:** vascular injury (MESH:D057772), nerve damage (MESH:D000080902), tremor (MESH:D014202), tumor (MESH:D009369), AI (MESH:C538142)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12968422/full.md

## References

69 references — full list in the complete paper: https://tomesphere.com/paper/PMC12968422/full.md

---
Source: https://tomesphere.com/paper/PMC12968422